4. Identify the reagents you would use to perform the following transformation: (a) Ethanol + Acetic acid (b) Toluene + Benzoic acid (c) Benzene + Benzoic acid (d) 1-Bromobutane- Pentanoic acid (e) Ethylbenzene -→ Benzoic acid (f) Bromocyclohexane + Cyclohexanecarboxylic acid
4. Identify the reagents you would use to perform the following transformation: (a) Ethanol + Acetic acid (b) Toluene + Benzoic acid (c) Benzene + Benzoic acid (d) 1-Bromobutane- Pentanoic acid (e) Ethylbenzene -→ Benzoic acid (f) Bromocyclohexane + Cyclohexanecarboxylic acid
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:A mechanism for this process is shown below:
H
0=c=o:
In the first step, the Grignard reagent attacks the electrophilic center of carbon dioxide, generating a
carboxylate ion. Treating the carboxylate ion with a proton source affords the carboxylic acid. These
two steps occur separately, as the proton source is not compatible with the Grignard reagent and can
only be introduced after the Grignard reaction is complete. This reaction provides us with another
two-step process for converting an alkyl (or vinyl or aryl) halide to a carboxylic acid.
Br
„MgBr
Mg
1) Co,
OH
2) H,0
4. Identify the reagents you would use to perform the following transformation:
(a) Ethanol + Acetic acid
(b) Toluene + Benzoic acid
(c) Benzene + Benzoic acid
(d) 1-Bromobutane → Pentanoic acid
(e) Ethylbenzene + Benzoic acid
(f) Bromocyclohexane + Cyclohexanecarboxylic acid
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