4. Identify the reagents you would use to perform the following transformation: (a) Ethanol + Acetic acid (b) Toluene + Benzoic acid (c) Benzene + Benzoic acid (d) 1-Bromobutane- Pentanoic acid (e) Ethylbenzene -→ Benzoic acid (f) Bromocyclohexane + Cyclohexanecarboxylic acid

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Chapter1: Chemical Foundations
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Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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A mechanism for this process is shown below:
H
0=c=o:
In the first step, the Grignard reagent attacks the electrophilic center of carbon dioxide, generating a
carboxylate ion. Treating the carboxylate ion with a proton source affords the carboxylic acid. These
two steps occur separately, as the proton source is not compatible with the Grignard reagent and can
only be introduced after the Grignard reaction is complete. This reaction provides us with another
two-step process for converting an alkyl (or vinyl or aryl) halide to a carboxylic acid.
Br
„MgBr
Mg
1) Co,
OH
2) H,0
4. Identify the reagents you would use to perform the following transformation:
(a) Ethanol + Acetic acid
(b) Toluene + Benzoic acid
(c) Benzene + Benzoic acid
(d) 1-Bromobutane → Pentanoic acid
(e) Ethylbenzene + Benzoic acid
(f) Bromocyclohexane + Cyclohexanecarboxylic acid
Transcribed Image Text:A mechanism for this process is shown below: H 0=c=o: In the first step, the Grignard reagent attacks the electrophilic center of carbon dioxide, generating a carboxylate ion. Treating the carboxylate ion with a proton source affords the carboxylic acid. These two steps occur separately, as the proton source is not compatible with the Grignard reagent and can only be introduced after the Grignard reaction is complete. This reaction provides us with another two-step process for converting an alkyl (or vinyl or aryl) halide to a carboxylic acid. Br „MgBr Mg 1) Co, OH 2) H,0 4. Identify the reagents you would use to perform the following transformation: (a) Ethanol + Acetic acid (b) Toluene + Benzoic acid (c) Benzene + Benzoic acid (d) 1-Bromobutane → Pentanoic acid (e) Ethylbenzene + Benzoic acid (f) Bromocyclohexane + Cyclohexanecarboxylic acid
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