4. Consider a pair of monozygotic twins, both are XY individuals (monozygotic = originated from the same zygote). One was healthy and the other showed symptoms of hemophilia related to loss-of-function of F8 (recall F8 locus is on the X chromosome, not in the pseudo autosomal region). a. Propose a way that these two twins have a different F8 phenotype despite arising from the same zygote? b. Consider XX monozygotic twins that came from a zygote that was +/- for the F8 locus. Is it possible that a mitotic non-disjunction could result in one twin developing hemophilia and the other not have hemophilia? Use a drawing to help explain your answer.
4. Consider a pair of monozygotic twins, both are XY individuals (monozygotic = originated from the same zygote). One was healthy and the other showed symptoms of hemophilia related to loss-of-function of F8 (recall F8 locus is on the X chromosome, not in the pseudo autosomal region). a. Propose a way that these two twins have a different F8 phenotype despite arising from the same zygote? b. Consider XX monozygotic twins that came from a zygote that was +/- for the F8 locus. Is it possible that a mitotic non-disjunction could result in one twin developing hemophilia and the other not have hemophilia? Use a drawing to help explain your answer.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
Related questions
Question
Question in photo
Transcribed Image Text:4. Consider a pair of monozygotic twins, both are XY individuals (monozygotic = originated
from the same zygote). One was healthy and the other showed symptoms of hemophilia
related to loss-of-function of F8 (recall F8 locus is on the X chromosome, not in the pseudo
autosomal region).
a. Propose a way that these two twins have a different F8 phenotype despite arising from
the same zygote?
b. Consider XX monozygotic twins that came from a zygote that was +/- for the F8 locus. Is
it possible that a mitotic non-disjunction could result in one twin developing hemophilia
and the other not have hemophilia? Use a drawing to help explain your answer.
Expert Solution
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
This is a popular solution!
Trending now
This is a popular solution!
Step by step
Solved in 4 steps with 1 images
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education