4. A clinical trial is conducted comparing a new pain reliever for arthritis to a placebo. Participants are ran- domly assigned to receive the new treatment or a placebo, and the outcome is pain relief within 30 min- utes. The data are shown in Table 7-8. Is there a sig- nificant difference in the proportions of patients reporting pain relief Run the test at a 5% level of sig- nificance. TABLE 7-8 Data for Practice Problem 4 5. A dinical trial is planned to compare an experimen- tal medication designed to lower blood pressure to a placebo. Before starting the trial, a pilot study is con- ducted involving seven participants. The objective of the study is to assess how systolic blood pressure changes over time untreated. Systolic blood pressures are measured at baseline and again 4 weeks later. Is there a statistically significant difference in blood Pain Relief No Pain Relief New Medication Placebo 44

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4. A clinical trial is conducted comparing a new pain
reliever for arthritis to a placebo. Participants are ran-
domly assigned to receive the new treatment or a
placebo, and the outcome is pain relief within 30 min-
utes. The data are shown in Table 7-8. Is there a sig-
nificant difference in the proportions of patients
reporting pain relief? Run the test at a 59% level of sig-
TABLE 7-8 Data for Practice Problem 4
nificance.
5. A clinical trial is planned to compare an experimen-
tal medication designed to lower blood pressure to a
placebo. Before starting the trial, a pilot study is con-
ducted involving seven participants. The objective of
the study is to assess how systolic blood pressure
changes over time untreated. Systolic blood pressures
are measured at baseline and again 4 weeks later. Is
there a statistically significant difference in blood
pressures over time? Run the test at a 5% level of sig-
nificance.
Pain Relief
No Pain Relief
New Medication
44
76
Placebo
21
99
TABLE 7-9 Data for Practice Problem 6
Baseline
120
145
130
160
152
Placebo
New Medication
143
126
134
114
4 weeks
122
142
135
158
155
143
117
140
130
148
Transcribed Image Text:Bsenot wOK E per CURED Adobe Acrobat he D Fle ton View Window Help Home Tools 72410217 W 1e O Share 4. A clinical trial is conducted comparing a new pain reliever for arthritis to a placebo. Participants are ran- domly assigned to receive the new treatment or a placebo, and the outcome is pain relief within 30 min- utes. The data are shown in Table 7-8. Is there a sig- nificant difference in the proportions of patients reporting pain relief? Run the test at a 59% level of sig- TABLE 7-8 Data for Practice Problem 4 nificance. 5. A clinical trial is planned to compare an experimen- tal medication designed to lower blood pressure to a placebo. Before starting the trial, a pilot study is con- ducted involving seven participants. The objective of the study is to assess how systolic blood pressure changes over time untreated. Systolic blood pressures are measured at baseline and again 4 weeks later. Is there a statistically significant difference in blood pressures over time? Run the test at a 5% level of sig- nificance. Pain Relief No Pain Relief New Medication 44 76 Placebo 21 99 TABLE 7-9 Data for Practice Problem 6 Baseline 120 145 130 160 152 Placebo New Medication 143 126 134 114 4 weeks 122 142 135 158 155 143 117 140 130 148
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6. A hypertension trial is mounted, and 12 participants
are randomly assigned to receive either a new med-
ication or a placebo. Each participant takes the as-
150
122
160
128
Transcribed Image Text:sreoT wOKc per CURED - Adobe Acrobat he DC Fle ton View Window Help Home Tools 11/ 231 14 O Share 6. A hypertension trial is mounted, and 12 participants are randomly assigned to receive either a new med- ication or a placebo. Each participant takes the as- 150 122 160 128
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