4) When a mixture of two different compounds both containing a hydrogens are placed under acidic or basic conditions, crossed aldol products can be formed. By either self-condensation or cross condensations. Draw the 4 aldol and 4 aB-unsaturated ketones that can be made from the following mixed system. -OH 4 products One way to control this is by either having only one compound with a hydrogens or by reacting the desired nucleophile with lithium diisopropylamide (LDA) before addition of second carbonyl. The issue here is that this reaction stops at the aldol unless excess base is used. 2. он LDA OH heat Show a synthetic scheme of how to use the following carbonyls to control the formation of each cross product (i.e. each as nucleophile and electrophile, two reactions). and

4) When a mixture of two different compounds both containing a hydrogens are placed under acidic or basic conditions, crossed aldol products can be formed. By either self-condensation or cross condensations. Draw the 4 aldol and 4 aB-unsaturated ketones that can be made from the following mixed system. -OH 4 products One way to control this is by either having only one compound with a hydrogens or by reacting the desired nucleophile with lithium diisopropylamide (LDA) before addition of second carbonyl. The issue here is that this reaction stops at the aldol unless excess base is used. 2. он LDA OH heat Show a synthetic scheme of how to use the following carbonyls to control the formation of each cross product (i.e. each as nucleophile and electrophile, two reactions). and

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

See similar textbooks

Similar questions

Draw the major product of the aldol condensation reaction between two of these ketones with the conditions provided. Ignore inorganic byproducts. O 1. NaOH, heat 2. Neutralizing work-up Drawing ด P
Which reagent(s) will result in the nucleophile attacking the more substituted side of an epoxide? Choose all that apply. O1. O1. LICH2CH3 I. HCI II. H20, H2SO4 IV. LIAIH4
Part 1 - Draw the full mechanism for the cross-aldol reaction between acetone and benzaldehyde Part 2 - Draw the product that would form if we added only one mole each of acetone and benzaldehyde. Part 3 - After forming the initial product, we see the elimination of water to give the final product as a solid that we collect. What drives this product formation?
You determine the bimolecular rate constant k for a set of SN2 reactions. Based on your understanding of how the nucleophile effects the rate constant for an SN2 reaction, drag and drop the nucleophiles into the correct rows in the table below. Alkyl halide Nucleophile k / L mol-1 s-1 CI 0.011 -CI 0.045 0.074 0.095 -NH2 -NH2 >-NH2 -NH2 -NH2
The enolate of an ester can be treated with a ketone to give a beta-hydroxy ester. Draw a mechanism for this aldol-like reaction. For the mechanism, draw the curved arrows as needed. Include lone pairs and charges in your answer. Do not draw out any hydrogen explicitly in your products. Do not use abbreviations such as Me or Ph. EtO 1) LDA 2) ΕΙΟ OH श्र Step 1 * Incorrect. Which of the mechanistic steps is shown in this step of the mechanism? Draw step 1 of the mechanism. HC CH CH3 CH3 Edit Drawing CH3
HO .OH cat. H2SO4 H₂O cat. H2SO4 Complete both mechanisms above. BRIEFLY explain how the different reaction conditions (in the presence of acid) result in different products being formed. How does equilibrium play a role?
6. For the following reaction, draw all of the synthetic intermediates that are formed in each step, including the final product. 1. H2SO4 2. mCPBA 3. MgBr-CH2CH3 4. H20 HO.
Draw an alkyl bromide that would produce ONLY the following alkene in an E2 elimination. Ignore any inorganic byproducts.