4) Advanced electron pushing problems. Provide a proper electron pushing mechanism that accounts for the product show using curved-arrow formalism. Molecular models may be of assistance in these problems. a) The following synthetic intermediate was prepared by Prof. Samuel J. Danishefsky and co- workers towards the guanacastapene family of terpene natural products. step 2) only; OH 1) LIHMDS, THF 2) Eschenmoser's Salt 3) mCPBA, DCM 1) Cl3CCN, TEA 2) A HN CS Cann CC13

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4) Advanced electron pushing problems.
Provide a proper electron pushing mechanism that accounts for the product show using
curved-arrow formalism. Molecular models may be of assistance in these problems.
a) The following synthetic intermediate was prepared by Prof. Samuel J. Danishefsky and co-
workers towards the guanacastapene family of terpene natural products.
HO
b) step 2) only;
OH
1) LIHMDS, THF
2) Eschenmoser's
Salt
3) mCPBA, DCM
1) Cl3CCN, TEA
2) Δ
HN
CS CamScanner
CC13
Transcribed Image Text:4) Advanced electron pushing problems. Provide a proper electron pushing mechanism that accounts for the product show using curved-arrow formalism. Molecular models may be of assistance in these problems. a) The following synthetic intermediate was prepared by Prof. Samuel J. Danishefsky and co- workers towards the guanacastapene family of terpene natural products. HO b) step 2) only; OH 1) LIHMDS, THF 2) Eschenmoser's Salt 3) mCPBA, DCM 1) Cl3CCN, TEA 2) Δ HN CS CamScanner CC13
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