3. Which would be the major product(s) of the following reaction? H3CO H3COO NO₂ H3CO. II HNO3 H₂SO4 NO₂ a) | b) II c) III e) I and III in roughly equal amounts. ? H3COO HO3S III d) I and II in roughly equal amounts.
Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
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H3COO
H3CO
NO₂
H3CO
II
HNO3
H₂SO4
NO₂
a) |
b) ll
c) III
e) I and III in roughly equal amounts.
?
H3CO.
HO3S
III
40
15
d) I and II in roughly equal amounts."
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