3. Using 2-methyloxirane and 2-bromopropane as your only sources of carbon, show how you would synthesize 4-methyl-2-pentanone. Show all reagents and conditions and synthetic intermediates, but you do not need to draw any curved arrows. D 2-methyloxirane Br i 2-bromopropane 4. The reaction of the epoxide with methoxide produces one of the two constitutional isomers of methoxy-methylcyclopentanol shown below. Write the steps in the mechanism for this process. Be sure to show the following: (1) the structure of any intermediates that are formed during the mechanism, (2), what, if anything, is added or lost during each step of the mechanism, (3) any non-zero formal charges found on the structures that you write. REMEMBER: You may not use any materials except those that are given in the equation. H₂C NaOMe/MeOH OH 4-methyl-2-pentanone -or- X -OH

3. Using 2-methyloxirane and 2-bromopropane as your only sources of carbon, show how you would synthesize 4-methyl-2-pentanone. Show all reagents and conditions and synthetic intermediates, but you do not need to draw any curved arrows. D 2-methyloxirane Br i 2-bromopropane 4. The reaction of the epoxide with methoxide produces one of the two constitutional isomers of methoxy-methylcyclopentanol shown below. Write the steps in the mechanism for this process. Be sure to show the following: (1) the structure of any intermediates that are formed during the mechanism, (2), what, if anything, is added or lost during each step of the mechanism, (3) any non-zero formal charges found on the structures that you write. REMEMBER: You may not use any materials except those that are given in the equation. H₂C NaOMe/MeOH OH 4-methyl-2-pentanone -or- X -OH

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

See similar textbooks

Similar questions

5. Propose a synthesis of 5-propyl-1,3-benzenediamine, starting from benzene. Be sure to carefully consider the order in which you introduce groups to benzene.
Can you please do c and d. Thanks!
Predict the product of the following Wittig reaction. Be sure your answer accounts for stereochemistry, where appropriate. If multiple stereoisomers form, be sure to draw all products using appropriate wedges and dashes.
from the list provided below, place the best reagent into each of the five reactions shown in order to complete the given synthetic conversion.
7. Draw the organic product/s you would expect in the reactions below. If no reaction write N.R. (Hint: think about the order of reactivity of each carboxylic acid derivative molecule towards nucleophilic acyl substitution). 0 HN(CH3)2 S 0 HSCH3 NHCH3
3. Provide the major organic product of the following EAS Reaction. Think about what reaction is happening (look at the reagents). Think about which ring is more reactive (activating group v deactivating group). Do the EAS making sure the group being addition goes in the correct position on the correct ring. HO -SO₂H HNO₂, H₂SO
2. Propose a reasonable mechanism for the following reactions. Label each reagent's role in the reaction. Assume aqueous work up to obtain neutral products. b. Ar- HO OH Ar ZnCl₂ Ar Hint: ZnCl₂ is a Lewis Acid.
2. Angie O'Plastee, a premed student aspiring to become a heart surgeon, wants to prepare 4-chloro-3- nitrobezenesulfonic acid starting with benzene. Which of the following synthetic plans would work best for her? Justify your answer. to Plan A: Plan B: Plan C: Plan D: Plan E: Plan F: Step 1: H₂SO4 Step 1: H₂SO4 Step 1: H₂SO4, HNO3 Step 1: H₂SO4, HNO3 Step 1: Cl₂, FeCl3 Step 1: Cl₂, FeCl3 Step:2. H₂SO4, HNO3 Step:2. Cl₂, FeCl3 Step:2. H₂SO4 Step:2 Cl₂, FeCl3. Step:2. H₂SO4 Step:2. H₂SO4, HNO3 Step 3. Cl₂, FeCl3 Step 3. H₂SO4, HNO3 Step 3. Cl₂, FeCl3 Step 3. H₂SO4 Step 3. H₂SO4, HNO3 Step 3. H₂SO4
Propose an efficient synthesis for the following transformation: The transformation above can be performed with some reagent or combination of the reagents listed below. Give the necessary reagents in the correct order, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one correct solution, provide just one answer. A. -COOH HO OH + acid D. H3O+, heat G. Na2Cr2O7, H₂SO4, H₂O J. SOCI₂ B. HS SH + acid E. [H*], CH3NH2 H. 1) LIAI(OR) 3H; 2) H3O+ K. PCC or DMP 요 C. + acid F. 1) Et₂CuLi; 2) H3O+ I.1) LIAIH4; 2) H3O+ L. RCO 3H
10. Propose a multi-step synthesis to prepare para-nitrotoluene from benzene. NOTE: You can just provide the description or name of the reaction, you do not have to provide the actual reagents.
For the following reaction with excess reagent, predict the product. Be sure your answer accounts for If multiple stereocenters are formed, be sure to draw all products using appropriate wedges and stereochemistry. dashes. H CH3 1. EtLi, Et₂0 2. H30*
1. Show examples and structures the order of reactivity in SN2? 2. Show some SN2 reactions with Bromo-Ethene. Give 9 examples of Nucleophiles Nu- 3. Rank the following compounds in order of their expected reactivity toward SN2 reaction CH3Br, CH3OTos, (CH3)2CHCI 4. Show with examples for the influence of solvents in the SN2 reaction. 5. Show the Mechanism of the SN1 Reaction with the proper Directions of the arrows?