3. The Mannich reaction can take many forms, including reactions where aromatic heterocycles are employed. Provide mechanisms for the reactions in the following sequence. Me Meo OMe MeN MeN MeN -Br MECN, 100 °C NaH, THF: Br H then 6M HCI Meo,C. Me Me MeO2C

3. The Mannich reaction can take many forms, including reactions where aromatic heterocycles are employed. Provide mechanisms for the reactions in the following sequence. Me Meo OMe MeN MeN MeN -Br MECN, 100 °C NaH, THF: Br H then 6M HCI Meo,C. Me Me MeO2C

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter17: Alcohols And Phenols

Section17.SE: Something Extra

Problem 60AP: Benzvl chloride can be converted into benzaldehvde by treatment with nitromethane and base. The...

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Question

Please help

Meo OMe
3. The Mannich reaction can take many forms, including reactions where aromatic heterocycles are employed. Provide
mechanisms for the reactions in the following sequence.
Me
Meo
MeN
H..
OMe
MeN-
N-
MeN
Br
МеCN, 100 "C
NaH, THF;
H
Br
then 6M HCI
Meo,C
Me
Me
MeO2C

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