3. Stoichiometric Calculations of Metabolic Process Consider the glycolysis of glucose where 20 μmol of glucose is used to initiate the EMP pathway. answer the following questions: a. Assume that you initiated the EMP pathway to produce dihydroxyacetene phosphate (DHAP). How many μmol of DHAP are produced from the initial amount of glucose? b. What if you instead took the EMP pathway to the end; how many μmol of pyruvate are produced from the same initial amount of glucose? c. Determine the amount of free-energy (based on the total ATP) released at the end of the EMP pathway under aerobic conditions from the initial amount of glucose
3. Stoichiometric Calculations of Metabolic Process Consider the glycolysis of glucose where 20 μmol of glucose is used to initiate the EMP pathway. answer the following questions: a. Assume that you initiated the EMP pathway to produce dihydroxyacetene phosphate (DHAP). How many μmol of DHAP are produced from the initial amount of glucose? b. What if you instead took the EMP pathway to the end; how many μmol of pyruvate are produced from the same initial amount of glucose? c. Determine the amount of free-energy (based on the total ATP) released at the end of the EMP pathway under aerobic conditions from the initial amount of glucose
Introduction to Chemical Engineering Thermodynamics
8th Edition
ISBN:9781259696527
Author:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Publisher:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Chapter1: Introduction
Section: Chapter Questions
Problem 1.1P
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Transcribed Image Text:3. Stoichiometric Calculations of Metabolic Process
Consider the glycolysis of
glucose where 20 μmol of glucose is used to initiate the EMP pathway.
answer the following questions:
a. Assume that you initiated the EMP pathway to produce dihydroxyacetene phosphate (DHAP).
How many μmol of DHAP are produced from the initial amount of glucose?
b. What if you instead took the EMP pathway to the end; how many μmol of pyruvate are
produced from the same initial amount of glucose?
c. Determine the amount of free-energy (based on the total ATP) released at the end of the EMP
pathway under aerobic conditions from the initial amount of glucose
Glycolysis pathway
1 Glucose + 2NAD + 2ADP + 2Pi→ 2 Pyruvate + 2NADH + 2 ATP + H₂O
A) 20 μmol * 2 = 40µmol of DHAP produced
B) 40 μmol of DHAP is still produced.
ATP
C) 20 μmol✶ 2
=
40μmol ATP
glucose
kJ
AG = -30.5. of ATP
mol
kJ
40μmol * -30.5. = -1220μJ
mol
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Step 1: Calculate moles of DHAP produced from the initial amount of glucose
VIEWStep 2: Calculate moles of DHAP produced from the initial amount of glucose
VIEWStep 3: Calculate moles of pyruvate produced from the same initial amount of glucose
VIEWStep 4: Determine the amount of free energy
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