3. Propose an efficient synthesis for the target molecule from the indicated starting material. Assume you have a good selection of other reagents including any inorganic compounds, benzene, and any organic compound containing 3 or fewer carbons. Make sure your synthesis provides a way to control the relative stereochemistry of the target molecule (but not the absolute stereochemistry). Write both a retrosynthetic analysis and the synthesis in the forward direction showing all necessary reagents and reaction conditions for each step. Me Ph OH Ph target Me Me ད starting material

3. Propose an efficient synthesis for the target molecule from the indicated starting material. Assume you have a good selection of other reagents including any inorganic compounds, benzene, and any organic compound containing 3 or fewer carbons. Make sure your synthesis provides a way to control the relative stereochemistry of the target molecule (but not the absolute stereochemistry). Write both a retrosynthetic analysis and the synthesis in the forward direction showing all necessary reagents and reaction conditions for each step. Me Ph OH Ph target Me Me ད starting material

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Using acetylene as your only source of carbon atoms, identify a synthetic route for the production of 1-bromobutane. First, select the reagents necessary for the transformation shown, using no more than four steps in the synthesis. In part 2, you will synthesize any carbon reagents (other than acetylene) that were used in the synthesis. The transformation above can be performed with some reagent or combination of the reagents listed below. Give the necessary reagent(s) in the correct order, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one correct solution, provide just one answer.
Propose an efficient synthesis for the given transformation. This transformation can be performed with some reagent or combination of the reagents listed below. Give the necessary reagent(s) in the correct order, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one correct solution, provide just one answer. A B E 1) &: 2) 1)A :2) Mg H2, Lindlar's cat. NaH F G H. J 1) MeMgBr; 2) H30* Na, NH3 (1) МСРВА 1) EtMgBr; 2) HBr (xs), heat (RCO3H) H3O+ K L M N dilute H2SÓ4 SOCI2, pyridine 1) BH3-THF; 2) H2O2, NaOH DMP or PCC EtBr
The following synthesis requires more than one step. Specify the reagents you would use to carry it out. Specify reagents using letters from the table, first reagent on the left. Example: ab CH3CH₂CH₂C=CH a b C d Br₂ CH31 CH3CH₂1 CH3CH₂CH₂Br The reagents are (in order of use): f ? CH3CH,CH,CHO e CH₂l2/Zn(Cu) / ether h Reagents H₂/ Lindlar catalyst g H₂ over Pd/C 1. BH3 in THF 2. H₂O₂ in NaOH i j k I 1. 03 2. Zn/H3O+ Li in NH3 KOH / ethanol NaNH2 / NH3
Propose an efficient synthesis.
7) Using the carbon-containing starting material(s), propose a synthesis the following retrosynthetic analysis. Provide structures for all intermediates. The carbon atoms in the product must originate from the starting material(s), but you may use as many equivalents of each starting material as you would like, and any reagent/reaction you know (note: no mechanisms are required). Br OH racemic = = + -Br
Design a multi-step synthesis of the target below, starting with benzene and cyclohexene. No additional carbon sources should be used for the carbons incorporated into the final product. Make sure to include all reagents/conditions and major organic products for each step in your synthesis. No mechanisms are needed.
Propose an efficient synthesis for the given transformation. OH This transformation can be performed with some reagent or combination of the reagents listed below. Give the necessary reagent(s) i the correct order, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one correct solution, provide just one answer. A Br₂, hv F 1) MeMgBr; 2) H3O+ K dilute H₂SO4 B 1); 2) H3O+ G Na, NH3 (1) L DMP or PCC 1); 2) H3O+ H MCPBA (RCO 3H) M SOCI2, pyridine D Mg, diethyl ether I 1) EtMgBr; 2) H3O+ N EtBr E H₂, Lindlar's cat. J HBr (xs), heat O 1) BH3-THF; 2) H₂O2, NaOH
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Starting with benzene and using any other necessary reagents of your choice, design a synthesis the following compound. Note: some of these problems have more than one plausible answer. H₂N The transformation above can be performed with some reagent or combination of the reagents listed below. Give the necessary reagents in the correct order, as a string of letters (without spaces or punctuation, such as "EBF"). If there is more than one correct solution, provide just one answer. A. Br₂, FeBra D. 1) Zn. HCI; 2) NaOH B. dilute H₂SO4 E. conc. fuming H₂SO C.HNO3, H₂SO4 F.CI, AICla
Synthesis / Retrosynthetic Analysis 5) Using the carbon containing starting material(s) provided, propose a synthetic scheme for the following target molecule. Provide structures for all intermediates. The carbon atoms in the product must originate from the starting material(s), but you may use as many equivalents of each starting material as you would like, and any reagent/reaction you know. (note: no mechanisms are required).
2
Which ones will be used?