**Exercise 3: Acetoacetic Ester Synthesis**Propose an acetoacetic ester synthesis to make 5-ethyl-6-methyl-2-heptanone.**Explanation:**This question asks you to design a synthetic route using acetoacetic ester. The goal is to create the specified ketone, 5-ethyl-6-methyl-2-heptanone, using known reagents and reaction steps. The acetoacetic ester synthesis typically involves:1. **Formation of an enolate ion** from the acetoacetic ester by treatment with a base.2. **Alkylation** of the enolate ion with an appropriate alkyl halide.3. **Hydrolysis and decarboxylation** of the resulting compound to yield the desired ketone.Consider the molecular structure of 5-ethyl-6-methyl-2-heptanone as you select which alkyl halides to use and ensure that the necessary carbon skeleton is constructed through the synthesis.

Acetoacetic ester or ethyl acetoacetate is an active methylene compound and thus help in various…

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3. Propose an acetoacetic ester synthesis to make 5-ethyl-6-methyl-2-heptanone.

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter23: Addition To A Carbonyl

Section: Chapter Questions

Problem 39CTQ

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