3. Hexane, shown below, has very poor solubility in water (-9 mg/L). hexane 2-hexanol OH HO 1,6-hexanediol OH a. Based on what you know about the hydrophobic effect, explain, in thermodynamic terms, why this is the case. Also, what do you think would happen (at both the macroscopic and microscopic levels) if you vigorously agitated a mixture of water and hexane (both liquids), and then let it rest? b. Two additional molecules other than hexane are also shown above, 2-hexanol and 1,6- hexanediol. Put these three molecules in order from most water-soluble to least water-soluble. c. Draw some of the hydrogen bonds that would occur between 1,6-hexanediol and water if this molecule were dissolved in an aqueous solution. Which atoms are H-bond donors, and which are acceptors?

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Please explain and solve question 3.

3. Hexane, shown below, has very poor solubility in water (-9 mg/L).
hexane
2-hexanol
OH
HO
1,6-hexanediol
OH
a. Based on what you know about the hydrophobic effect, explain, in thermodynamic terms, why this
is the case. Also, what do you think would happen (at both the macroscopic and microscopic
levels) if you vigorously agitated a mixture of water and hexane (both liquids), and then let it rest?
b. Two additional molecules other than hexane are also shown above, 2-hexanol and 1,6-
hexanediol. Put these three molecules in order from most water-soluble to least water-soluble.
c. Draw some of the hydrogen bonds that would occur between 1,6-hexanediol and water if this
molecule were dissolved in an aqueous solution. Which atoms are H-bond donors, and which are
acceptors?
Transcribed Image Text:3. Hexane, shown below, has very poor solubility in water (-9 mg/L). hexane 2-hexanol OH HO 1,6-hexanediol OH a. Based on what you know about the hydrophobic effect, explain, in thermodynamic terms, why this is the case. Also, what do you think would happen (at both the macroscopic and microscopic levels) if you vigorously agitated a mixture of water and hexane (both liquids), and then let it rest? b. Two additional molecules other than hexane are also shown above, 2-hexanol and 1,6- hexanediol. Put these three molecules in order from most water-soluble to least water-soluble. c. Draw some of the hydrogen bonds that would occur between 1,6-hexanediol and water if this molecule were dissolved in an aqueous solution. Which atoms are H-bond donors, and which are acceptors?
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