Homework Help is Here – Start Your Trial Now!
Science
Biochemistry
3. Glycogen phosphorylase converts glycogen into glucose monomers and is the rate limiting step in glycogenolysis (that will be treated later in the course). It catalyzes the following reaction: (a-1,4 glycogen chain), + P, (a-1,4 glycogen chain) 1 +a-D-glucose-1-phosphate a. Glycogen phosphorylase is a K-system allosteric enzyme. Draw a plot of the rate for Glycogen phosphorylase versus inorganic phosphate concentration. Explain why the curve you drew is similar or different from the normal Michaelis-Menten curve. b. Based on the fact that glycogen phosphorylase is a k-system inhibitor and the plot you drew for part a, do you expect the enzyme to be a monomer or a dimer (note that a

3. Glycogen phosphorylase converts glycogen into glucose monomers and is the rate limiting step in glycogenolysis (that will be treated later in the course). It catalyzes the following reaction: (a-1,4 glycogen chain), + P, (a-1,4 glycogen chain) 1 +a-D-glucose-1-phosphate a. Glycogen phosphorylase is a K-system allosteric enzyme. Draw a plot of the rate for Glycogen phosphorylase versus inorganic phosphate concentration. Explain why the curve you drew is similar or different from the normal Michaelis-Menten curve. b. Based on the fact that glycogen phosphorylase is a k-system inhibitor and the plot you drew for part a, do you expect the enzyme to be a monomer or a dimer (note that a

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
See similar textbooks
icon
Related questions
Question

Please answer completely will give rating surely

All questions answers needed

single glycogen phosphorylase chain has I single Pi substrate binding site)? c. Given that ATP and Glucose is an inhibitor of glycogen phosphorylase and AMP is a positive effector draw a new curve showing schematically the rate of glycogen phosphorylase versus phosphate concentration in the presence of Glucose and AMP, and explain how and why the curve is affected. d. Considering that glycogenolysis helps make glucose stored as glycogen available for glycolysis, what rational might explain why ATP and glucose are inhibitors and AMP a positive effector? e. If glycogen phosphorylase was a V-system enzyme how would a plot of plot of the rate for Glycogen phosphorylase versus inorganic phosphate concentration change in the presence of ATP and AMP?
Transcribed Image Text:single glycogen phosphorylase chain has I single Pi substrate binding site)? c. Given that ATP and Glucose is an inhibitor of glycogen phosphorylase and AMP is a positive effector draw a new curve showing schematically the rate of glycogen phosphorylase versus phosphate concentration in the presence of Glucose and AMP, and explain how and why the curve is affected. d. Considering that glycogenolysis helps make glucose stored as glycogen available for glycolysis, what rational might explain why ATP and glucose are inhibitors and AMP a positive effector? e. If glycogen phosphorylase was a V-system enzyme how would a plot of plot of the rate for Glycogen phosphorylase versus inorganic phosphate concentration change in the presence of ATP and AMP?
3. Glycogen phosphorylase converts glycogen into glucose monomers and is the rate limiting step in glycogenolysis (that will be treated later in the course). It catalyzes the following reaction: (a-1,4 glycogen chain), + P,= (a-1,4 glycogen chain).-1+a-D-glucose-1-phosphate a. Glycogen phosphorylase is a K-system allosteric enzyme. Draw a plot of the rate for Glycogen phosphorylase versus inorganic phosphate concentration. Explain why the curve you drew is similar or different from the normal Michaelis-Menten curve. b. Based on the fact that glycogen phosphorylase is a k-system inhibitor and the plot you drew for part a, do you expect the enzyme to be a monomer or a dimer (note that a
Transcribed Image Text:3. Glycogen phosphorylase converts glycogen into glucose monomers and is the rate limiting step in glycogenolysis (that will be treated later in the course). It catalyzes the following reaction: (a-1,4 glycogen chain), + P,= (a-1,4 glycogen chain).-1+a-D-glucose-1-phosphate a. Glycogen phosphorylase is a K-system allosteric enzyme. Draw a plot of the rate for Glycogen phosphorylase versus inorganic phosphate concentration. Explain why the curve you drew is similar or different from the normal Michaelis-Menten curve. b. Based on the fact that glycogen phosphorylase is a k-system inhibitor and the plot you drew for part a, do you expect the enzyme to be a monomer or a dimer (note that a
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 2 steps with 2 images

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Knowledge Booster
Medical terminologies
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.
Similar questions
Recommended textbooks for you
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781319114671
Author:
Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:
W. H. Freeman
Lehninger Principles of Biochemistry
Lehninger Principles of Biochemistry
Biochemistry
ISBN:
9781464126116
Author:
David L. Nelson, Michael M. Cox
Publisher:
W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul…
Fundamentals of Biochemistry: Life at the Molecul…
Biochemistry
ISBN:
9781118918401
Author:
Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:
WILEY
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305961135
Author:
Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:
Cengage Learning
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning
Fundamentals of General, Organic, and Biological …
Fundamentals of General, Organic, and Biological …
Biochemistry
ISBN:
9780134015187
Author:
John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:
PEARSON
SEE MORE TEXTBOOKS