3. Blind fish are found in caves all over Northeastern Mexico. These fish are closely related to fish with normal vision that live in well-lit environments nearby. An evolutionary biologist is interested in the genetic basis of sight loss in the cave dwelling fish. After determining that blindness is a recessive trait in fish from two different caves, she crosses a blind fish from cave 1 to a blind fish from cave 2, and finds that 75% of the offspring are blind, and 25% are sighted. Which of the following interpretations fits this result best? Can two be possible? Fully explain your reasoning. A. Blindness in the fish from cave 1 vs. cave 2 is caused by fully penetrant mutations in the same gene. B. Blindness in the fishes from cave 1 vs. cave 2 are caused by mutations in the same gene that are not fully penetrant. C. Blindness in the fishes from cave 1 vs. cave 2 are caused by mutations in different genes. Wildtype or mutant aalleles of these genes may not be fully penetrant.

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### Genetic Analysis of Blind Fish in Northeastern Mexico

**Question 3.**

Blind fish are found in caves all over Northeastern Mexico. These fish are closely related to fish with normal vision that live in well-lit environments nearby. An evolutionary biologist is interested in the genetic basis of sight loss in the cave-dwelling fish. After determining that blindness is a recessive trait in fish from two different caves, she crosses a blind fish from cave 1 with a blind fish from cave 2, and finds that **75% of the offspring are blind, and 25% are sighted**. Which of the following interpretations fits this result best? Can two be possible? Fully explain your reasoning.

**A.** Blindness in the fish from cave 1 vs. cave 2 is caused by fully penetrant mutations in the same gene.

**B.** Blindness in the fish from cave 1 vs. cave 2 are caused by mutations in the same gene that are not fully penetrant.

**C.** Blindness in the fish from cave 1 vs. cave 2 are caused by mutations in different genes. Wildtype or mutant alleles of these genes may not be fully penetrant.
Transcribed Image Text:### Genetic Analysis of Blind Fish in Northeastern Mexico **Question 3.** Blind fish are found in caves all over Northeastern Mexico. These fish are closely related to fish with normal vision that live in well-lit environments nearby. An evolutionary biologist is interested in the genetic basis of sight loss in the cave-dwelling fish. After determining that blindness is a recessive trait in fish from two different caves, she crosses a blind fish from cave 1 with a blind fish from cave 2, and finds that **75% of the offspring are blind, and 25% are sighted**. Which of the following interpretations fits this result best? Can two be possible? Fully explain your reasoning. **A.** Blindness in the fish from cave 1 vs. cave 2 is caused by fully penetrant mutations in the same gene. **B.** Blindness in the fish from cave 1 vs. cave 2 are caused by mutations in the same gene that are not fully penetrant. **C.** Blindness in the fish from cave 1 vs. cave 2 are caused by mutations in different genes. Wildtype or mutant alleles of these genes may not be fully penetrant.
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