3- The mechanism for the ortho substitution of aniline is shown below. Using acetanilide, which is an activating group like aniline, shows the mechanism for para-addition. Include all resonance structures. Explain why para-addition, like ortho addition, is favored when an activating group is on the ring. NH2 E NH2 E NH2 O E : NH, E "ortho attack" @NH₂ E Additional resonance structure where all atoms I have an octet. This helps to stabilize the ortho pathway.

3- The mechanism for the ortho substitution of aniline is shown below. Using acetanilide, which is an activating group like aniline, shows the mechanism for para-addition. Include all resonance structures. Explain why para-addition, like ortho addition, is favored when an activating group is on the ring. NH2 E NH2 E NH2 O E : NH, E "ortho attack" @NH₂ E Additional resonance structure where all atoms I have an octet. This helps to stabilize the ortho pathway.

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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