27. SYNTHESIS! Propose a multistep synthesis for the following transformation. Use the starting material provided along with any general reagents, protecting groups, and alkyl halides of 6 carbons or fewer (organic reagents/protecting groups may have more than 6 carbons provided these carbons do not end up in the carbon framework of the final product). hom LOH hat

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Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.