Homework Help is Here – Start Your Trial Now!
Science
Biochemistry
26. Dietary triglycerides are hydrolyzed by pancreatic lipase, which is related to but distinct from lipase that functions in adipose tissue. Would you expect pancreatic lipase to be activated by glucagon? Why or why not?

26. Dietary triglycerides are hydrolyzed by pancreatic lipase, which is related to but distinct from lipase that functions in adipose tissue. Would you expect pancreatic lipase to be activated by glucagon? Why or why not?

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
See similar textbooks
icon
Related questions
Question

Please answer fast 

 

26. Dietary triglycerides are hydrolyzed by pancreatic lipase, which is related to but distinct from lipase that functions in adipose tissue. Would you expect pancreatic lipase to be activated by glucagon? Why or why not? 27. Pancreatic lipase is structurally similar to the protease chymotrypsin, and shares the same catalytic triad (asp-his-ser). Below is a diagram of the active site of pancreatic lipase with a triglyceride bound. Draw A) Draw arrows on this diagram to show the mechanism for the formation of the acyl intermediate B) Draw the acyl intermediate in the right hand box C) Draw arrows on the acyl intermediate to show the mechanism of its hydrolysis D) What type of catalysis is being played by the serine? By the histidine? What is the role of Phe77 and Leui53? Asp176 R His263 Ser152 .R R Phe7" R Leu153
Transcribed Image Text:26. Dietary triglycerides are hydrolyzed by pancreatic lipase, which is related to but distinct from lipase that functions in adipose tissue. Would you expect pancreatic lipase to be activated by glucagon? Why or why not? 27. Pancreatic lipase is structurally similar to the protease chymotrypsin, and shares the same catalytic triad (asp-his-ser). Below is a diagram of the active site of pancreatic lipase with a triglyceride bound. Draw A) Draw arrows on this diagram to show the mechanism for the formation of the acyl intermediate B) Draw the acyl intermediate in the right hand box C) Draw arrows on the acyl intermediate to show the mechanism of its hydrolysis D) What type of catalysis is being played by the serine? By the histidine? What is the role of Phe77 and Leui53? Asp176 R His263 Ser152 .R R Phe7" R Leu153
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 3 steps

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Recommended textbooks for you
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781319114671
Author:
Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:
W. H. Freeman
Lehninger Principles of Biochemistry
Lehninger Principles of Biochemistry
Biochemistry
ISBN:
9781464126116
Author:
David L. Nelson, Michael M. Cox
Publisher:
W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul…
Fundamentals of Biochemistry: Life at the Molecul…
Biochemistry
ISBN:
9781118918401
Author:
Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:
WILEY
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305961135
Author:
Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:
Cengage Learning
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning
Fundamentals of General, Organic, and Biological …
Fundamentals of General, Organic, and Biological …
Biochemistry
ISBN:
9780134015187
Author:
John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:
PEARSON
SEE MORE TEXTBOOKS