21. A 70-year-old man is brought to the emergency department because of a 3-day history of fever and progressive shortness of breath. He also has a history of cough productive of yellow sputum that has recently become thick and green. He has smoked 1 to 2 packs of cigarettes daily for 40 years. His temperature is 40°C (104°F), and respirations are 22/min. Physical examination shows decreased breath sounds. A chest x-ray shows right lower lobe infiltrates surrounding a 3-cm, rounded lesion containing an air-fluid level. Which of the following immune cell activities most likely predominates in the center of this lesion? A) B-lymphocyte antibody production B) Macrophage free-radical generation C) Natural killer cell-mediated killing D) Segmented neutrophil acid hydrolase activation E) T-lymphocyte perforin synthesis D
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- Case #4Following an automobile accident, a 19 year old male is admitted to the hospital. He has sustained multiple burns, severe pulmonary contusions, and has aspirated. He is admitted to the ICU, intubated and placed on a ventilator with initial settings ofA/C 500 x 16 1.0 +10 PEEP. A PAC is inserted and ABG’sare drawn after 30 minutes of mechanical ventilation. CXR reveals correct placement of the ETT andPAC the presence of bilateral infiltrates.pH = 7.53Hgb = 14 gmsPaCO2 = 35 mmHgPvO2 = 28 mmHgPaO2 = 33 mmHgSvO2 = 58 mmHgHCO3 = 26 mEq/LSaO2 = 78%PAC measurements reveal the following values:CVP = 12 mmHgBP = 140/80 mmHgPAP = 50/25 mmHgHR = 110 beats/minPCWP = 6 mmHgCO = 6.0 L/minPart 3: What is the arterial- venous oxygen content (Ca-vO2) difference for this patient?Part 4: Calculate the patient’s extraction ratio.Case: A 25-year-old female visits for a 6-month picture and refers to recurrent episodes of dyspnea, chest tightness and wheezing, as well as cough with fits, productive with mucohyaline sputum, without fever.Background: atopic dermatitis in childhood. Her mother is asthmatic and allergic to medications.TA: 120¨80 mmHg, HR: 85 lat. per min FR: 19 res per min. Sat.02 90%The vesicular murmur is present and diminished and has some isolated wheezing.a) What is the most important risk factor in this patient for developing asthma?b) What is the hypersensitivity mechanism by which asthma develops in this patient?c) What is the most important study to confirm the diagnosis of asthma and classify it?d) What would be the treatment of choice for the long-term control of this patient?1. A previously healthy 25-year-old-woman comes to the emergency department because of a 3-day history of fever, chest pain, and rapidly progressive shortness of breath. Use of an over-the-counter cold medication has not relieved her symptoms. She has no history of serious illness and takes no other medications. Her temperature is 40oC (104o F), pulse is 128/min and regular, respirations are 28/min and blood pressure is 80/54 mm Hg. Physical examination shows jugular venous distention and weak pulses in all extremities. Auscultation of the chest shows diffuse crackles bilaterally, muffled heart sounds, and a soft S2 gallop. After 30 minutes she goes into ventricular fibrillation and cannot be resuscitated. At autopsy, the heart is diffusely pale and floppy with focal petechiae, all chambers are markedly dilated.Histologic examination of cardiac tissue shows a lymphocytic infiltrate and myocardial necrosis. Which of the following infectious agents is the most likely cause these…
- 6- which PFT parameter below is a significant discrimination for restrictive pulmonary disease when compared to normal pulmonary function? A- FEV/FVC B- FRC C- ERV D- ICV.W, a 69-year-old male. You will address a postoperative client who has been non-compliant with ambulation and the use of his incentive spirometer. Ultimately, the client develops respiratory complications associated with pulmonary embolism. Clinical Picture: VW is a 69 year old male who presented to the ER 4 days ago for c/o nausea, vomiting and severe abdominal pain. He underwent emergency surgery for bowel perforation. PMHX: Cataracts, HTN Final DX: bowel perforation, s/p left hemicolectomy The scenario will begin with the charge nurse giving students a report on the patient. Chart Name: Vernon Watkins Age: 69 Gender: Male Weight: 80 kg Height: 5 feet, 10 inches Race: Caucasion Religion: Christian Wife: (major support) - Martha Watkins Allergies: Penicillin (hives) Immunizations: Current Current set of vitals on the chart: T: 98.6 HR: 100 RR: 21 BP: 146/88 SP02: 96% on RA LAB DATA: None available Provider's Orders Diet: Soft advance as tolerated Fall…Mrs. G HISTORY Mrs. G, a 62-year-old white woman, was seen in the emergency department for complaints of increasing shortness of breath. She stated that she had the flu approximately 1½ weeks earlier and that her breathing has been more difficult since that time. Her ankles have been swollen for the first time, and sleeping during this time has required "two pillows to support her." She stated that occasionally she awakens in the middle of the night noticeably short of breath. These episodes of nocturnal dyspnea are relieved by sitting up for several minutes. She has been producing ¼ cup of yellow sputum since the onset of the flu. Her exercise tolerance was 1 block but is now 20 feet. Mrs. G stated that 7 years ago her family physician told her she had pulmonary emphysema. Mrs. G started smoking at age 12 and smoked approximately 2 packs of cigarettes a day until she quit 2 years ago. Mrs. G took the following home medications: small-volume nebulizer (SVN) with metaproterenol four…
- 45. A 5-year-old girl with a history of recurrent infections since the age of 4 months is brought to the physician for a follow-up examination. She has had multiple episodes of pneumonia, sinusitis, otitis media, and diarrhea. She is at the 20th percentile for height and weight. Her temperature is 37.4°C (99.3°F). Mild crackles are heard bilaterally over the lower lung lobes. Laboratory studies show: Leukocyte count Segmented neutrophils Eosinophils 10,500/mm³ (N=5500-15,500) 57% 2% Lymphocytes 34% CD3+ T lymphocytes 67% CD19+ B lymphocytes 28% CD56+ natural killer cells 5% Monocytes 7% Serum IgA IgG IgM undetectable (N=14-159 mg/dL) 25 mg/dL (N=345-1236) 410 mg/dL (N=43-207) This patient most likely has an abnormality of which of the following immune system components? A) Activation-induced deaminase B) CD40 ligand OC) Class II MHC protein D) Common y chain of the interleukin-2 (IL-2) receptor E) Recombination-activating gene 1 F) Terminal complementexplain how the mantoux test for TB generates a positive result113. A 10-month-old girl develops a cough and grunting following a 3-day hospital stay for surgical repair of a cleft palate. Her temperature is 39.2°C (102.6°F), and respirations are 40/min. Crackles are heard over most lung fields, and breath sounds are decreased. There is a mild pleural rub in the right upper thorax. Her leukocyte count is 68,000/mm³ (85% segmented neutrophils, 10% bands, and less than 5% myeloblasts, promyelocytes, and myelocytes). Which of the following mechanisms most likely caused the increased leukocyte count in this patient? A) Accelerated release of cells from the bone marrow postmitotic reserve pool B) Decreased margination and rolling of circulating cells C) Increased production of myeloblasts in the spleen D) Shift in bone marrow from eosinophil production to segmented neutrophil production E) Transformation of myeloid stem cells
- Case #1Mrs. G, a 62-year-old female, was seen in the emergency department for complaints of increasing shortness of breath. Mrs. G states that seven years ago her family physician told her she had emphysema.At home she is on oxygen via nasal cannula at 1 lpm, and a small volume nebulizer with albuterol sulfate four times a day. Her vital signs are as follows: HR 108/minute, RR 28/minute, BP 142/80 mmHg.ABG results on a 24% venturi mask are:pH 7.32P a CO 2 62 mmHgP a O 2 50 mmHgHCO 3 30 mEq/lS a O 2 85%BE +5Hb 13g/dlETCO2 30 mmHgP B 740 mmHgPart 1: Calculate the patient’s dead space to tidal volume ratio and explain the significancePart 2: What is clinically happening to the patient?Mrs blaze a 68 years old female visit her primary care provider office she has not been feeling well. Mrs blaze tells the nurse that she has been experiencing regular episodes of shortness of breath and fatigue for the last 2 weeks she does not have fever or productive cough. Upon assessment the client states that she has been smoking one pack of cigarettes per day for the past 40 years. 1 explain the normal age related changes that are occurring in Mrs blaze respiratory system. 2. Explain the normal process of inspiration and expiration. 3. Describe the physiological process that is occurring when Mrs blaze becomes short of breath.Case # 1 Mrs. G, a 62-year-old female, was seen in the emergency department for complaints of increasing shortness of breath. Mrs. G states that seven years ago her family physician told her she had emphysema. At home she is on oxygen via nasal cannula at 1 lpm, and a small volume nebulizer with albuterol sulfate four times a day. Her vital signs are as follows: HR 108/minute, RR 28/minute, BP 142/80 mmHg. She's on a 24% venturi mask. Mrs. G's ABG results indicate partially compensated respiratory acidosis moderate hypoxemia with a base excess of +5. Part 1: PAO2 (oxygen partial pressure inside the alveoli) is 88.82 mmHg Part 2: Her actual A-a gradient is 38.62 mmHg.(Say normal for her 19.5) Part 3: Her actual dead space to tidal volume ratio is 0.52 (Say normal range: 0.25 to 0.40) What is clinically happening to the patient?