20 Effects of an appetite suppressant, continue 23.18 describes a study to determine if subjects with existing cardiovascular symptoms were at an increased risk of cardiovascular events while taking sibutramine. Do the data give good reason to think that there is a dif- ference between the proportions of treatment and pla- cebo subjects who experienced the primary outcome? (Note that sibutramine has not been available in the United States since the end of 2010 due to its manu- pre- facturer's concerns over increased risk of heart attack or stroke, although at the present time, it can still be purchased in other countries.) (a) State hypotheses, find the test statistic, and use either software or the bottom row of Table C for the P-value. Be sure to state your conclusion. (b) Explain simply why it was important to have a placebo group in this study.
20 Effects of an appetite suppressant, continue 23.18 describes a study to determine if subjects with existing cardiovascular symptoms were at an increased risk of cardiovascular events while taking sibutramine. Do the data give good reason to think that there is a dif- ference between the proportions of treatment and pla- cebo subjects who experienced the primary outcome? (Note that sibutramine has not been available in the United States since the end of 2010 due to its manu- pre- facturer's concerns over increased risk of heart attack or stroke, although at the present time, it can still be purchased in other countries.) (a) State hypotheses, find the test statistic, and use either software or the bottom row of Table C for the P-value. Be sure to state your conclusion. (b) Explain simply why it was important to have a placebo group in this study.
A First Course in Probability (10th Edition)
10th Edition
ISBN:9780134753119
Author:Sheldon Ross
Publisher:Sheldon Ross
Chapter1: Combinatorial Analysis
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Problem 1.1P: a. How many different 7-place license plates are possible if the first 2 places are for letters and...
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23.20 is what needs answerd the other is just info for it please use calculator method to answer ti83 or 84
Transcribed Image Text:3.20 Effects of an appetite suppressant, continue
23.18 describes a study to determine if subjects with
existing cardiovascular symptoms were at an increased
risk of cardiovascular events while taking sibutramine.
Do the data give good reason to think that there is a dif-
ference between the proportions of treatment and pla-
cebo subjects who experienced the primary outcome?
(Note that sibutramine has not been available in the
United States since the end of 2010 due to its manu-
pre-
facturer's concerns over increased risk of heart attack
or stroke, although at the present time, it can still be
purchased in other countries.)
(a) State hypotheses, find the test statistic, and use
either software or the bottom row of Table C for the
P-value. Be sure to state your conclusion.
(b) Explain simply why it was important to have a
placebo group in this study.
Transcribed Image Text:, one
dence
(c) is reasonably
inference are met.
(a) bo
(b) po = 0.368 and ,,
%3D
val for the difference between the proportion of rats
that succeed when given M and the prop on shat
succeed without it is
mples
de pooled sample proportion of respondents who ate
on all seven days before the survey is
||
23.16 (Optional topic) The plus four 90% confidence inrex
23.11
(b) = 0.368.
(c) p = 0.396.
%3D
(a) § = 0.338.
(a) 0.455 0.312.
ent.
the
(b) 0.417 0.304.
ers
(c) 0.417 0.185.
daily is
(c) z = 4.94.
ple
(b) 3.78.
on
(a) 2.45.
HAPTER 23 EXERCISES
Ten asing
che langesample methods of this chapter, be sure to check that
to
the drug. The study included 9804 overweight or obese
subjects with preexisting cardiovascular disease and/or
type 2 diabetes. The subjects were randomly assigned to
sibutramine (4906 subjects) or a placebo (4898 subjects)
in a double-blind fashion. The primary outcome mea-
sured was the occurrence of any of the following events:
nonfatal myocardial infarction or stroke, resuscitation
after cardiac arrest, or cardiovascular death. The primary
outcome was observed in 561 subjects in the sibutra-
mine group and 490 subjects in the placebo group."
(a) Find the proportion of subjects experiencing the
primary outcome for both the sibutramine and
placebo groups.
te
dinas for their use are met ana to state youT conclusions in context
7 Truthfulness in online profiles. Many teens have posted
profiles
on a social-networking website. A sample survey
n 2007 asked a random sample of teens with online
rofiles if they included false information in their pro-
files. Of 170 younger teens (aged 12 to 14), 117 said
Of 317 older teens (aged 15 to 17), 152 said yes."
yes.
17
(a) Do these samples satisfy the guidelines for the large-
sample confidence interval?
6 Give a 95% confidence interval for the difference
between the proportions of younger and older teens
who include false information in their online profiles.
18 Effects of an appetite suppressant. Subjects with pre-
sting cardiovascular symptoms who were receiving
stoutramine, an appetite suppressant, were found to be
a increased risk of cardiovascular events while taking
(b) Can we safely use the large-sample confidence inter-
val for comparing the proportions of sibutramine
and placebo subjects who experienced the primary
outcome! Explain.
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