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2. What is the pH in stomach? Is it an acidic or alkaline environment?

2. What is the pH in stomach? Is it an acidic or alkaline environment?

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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1. What functional groups could potentially increase water solubility? 2. What is the pH in stomach? Is it an acidic or alkaline environment? 3. Which functional groups you listed in Q1 might work better in the stomach? Why? 4. Given that the benzene rings are the key part that is responsible for the functionality of this drug, where will you place the functional groups (the ones you chose in Q3) for this molecule?
Transcribed Image Text:1. What functional groups could potentially increase water solubility? 2. What is the pH in stomach? Is it an acidic or alkaline environment? 3. Which functional groups you listed in Q1 might work better in the stomach? Why? 4. Given that the benzene rings are the key part that is responsible for the functionality of this drug, where will you place the functional groups (the ones you chose in Q3) for this molecule?
Please modify the structure of this drug (tamoxifen) to make it water-soluble and easy to be absorbed in stomach. H3C, N. ČH3 CH3
Transcribed Image Text:Please modify the structure of this drug (tamoxifen) to make it water-soluble and easy to be absorbed in stomach. H3C, N. ČH3 CH3
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