2. Furan and maleimide, shown below, react to produce and adduct via a Diels-Alder reaction. At 25°C the isomer produced is the endo product, however at 90°C the exo isomer predominates. Additional studies have shown that at 90°C the equilibrium between the endo and exo products favors the exo isomer. a) Draw each isomeric product, endo and exo. furan: O maleimide: b) Which isomer would you expect to usually form in this reaction? Why is that isomer usually preferred? N-H c) Is your answer to question 4(b) dependent on a kinetically or thermodynamically controlled reaction? d) Explain why the endo isomer predominates when the reaction takes place at 25°C and why the exo isomer at 90°C.
Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
Can u pls explain what endo and exo is and which one is dominant? And and what kinetically and
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