2. Below is the structure of an anti-inflammatory drug: F == Ο NH2 F N. N CH₂ A) How many rings are able to undergo electrophilic aromatic substitution (EARS)? ( B) Which of the rings is/are ACTIVATED for EARS? Encircle it/them on the structure. C) For each ring in B, answer the following statement: "The ring is activated because its substituent is (A. electron-donating; B. electron- withdrawing) through (A. inductive; B. resonance) effects. D) Which of the rings is/are DEACTIVATED for EARS? Box it/them on the structure. E) For each ring in D, answer the following statement: "The ring is deactivated because its substituent is (A. electron-donating; B. electron-withdrawing) through (A. inductive; B. resonance) effects. F) Draw the structure of a plausible product when this compound undergoes monobromination.

2. Below is the structure of an anti-inflammatory drug: F == Ο NH2 F N. N CH₂ A) How many rings are able to undergo electrophilic aromatic substitution (EARS)? ( B) Which of the rings is/are ACTIVATED for EARS? Encircle it/them on the structure. C) For each ring in B, answer the following statement: "The ring is activated because its substituent is (A. electron-donating; B. electron- withdrawing) through (A. inductive; B. resonance) effects. D) Which of the rings is/are DEACTIVATED for EARS? Box it/them on the structure. E) For each ring in D, answer the following statement: "The ring is deactivated because its substituent is (A. electron-donating; B. electron-withdrawing) through (A. inductive; B. resonance) effects. F) Draw the structure of a plausible product when this compound undergoes monobromination.

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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