2. a. Dehydration of this alcohol with POCI, and pyridine produces a single alkene product. Show the mechanism of the reaction and specify the alkene product. Note that "pyridine" is a soluble organic base. OH CH₂ POCI, pyridine b. Predict the product of this reaction KOC(CH₂) DMSO (C₁4H₁0₁) -Br Propose a mechanism that explains formation of these products from 2,2-dimethylcyclohexa You must show the intermediate structure from which the two products could form. OH CH₂ CH₂ CH₂ heat CH₂ CH₂ CH₂
Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
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