2. (a) A Markov chain X = {X, 0} is used for a competing risk analysis based on the following simple diagram with the respective transition rates H E1 7 5 E2 Figure 1: Transition diagram of a simple competing risk model. where H represents a healthy state, E₁ event of interest, and E2 other type of exit. i. Write down the intensity matrix of the Markov chain. ii. Find the transition probability Phe₁(t) = P(X₁ = E₁|X0 = H) of moving from a healthy state to the event of interest. iii. Find the expected remaining lifetime of a healthy subject. = (b) From the observations of sample paths of Markov chain X {X, t≥ 0} with state space S = {1,2,3}, the number of transitions Nij between states i, j = S and the length of time Z; spent in each state i = S are reported in the matrices below 0 20 30 10 N = 40 0 50 10 20 0 Z = 20 5 Elements qij of the intensity matrix Q is found as the maximizer of likelihood function 3 3 L({ij}) = [[((ij) i=1 j#i i. Find the estimate 7i; of the intensity qij. ii. Use the given observations to find an estimate of the intensity matrix Q.

Elementary Linear Algebra (MindTap Course List)
8th Edition
ISBN:9781305658004
Author:Ron Larson
Publisher:Ron Larson
Chapter2: Matrices
Section2.5: Markov Chain
Problem 47E: Explain how you can determine the steady state matrix X of an absorbing Markov chain by inspection.
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2. (a) A Markov chain X = {X, 0} is used for a competing risk analysis based on the
following simple diagram with the respective transition rates
H
E1
7
5
E2
Figure 1: Transition diagram of a simple competing risk model.
where H represents a healthy state, E₁ event of interest, and E2 other type of exit.
i. Write down the intensity matrix of the Markov chain.
ii. Find the transition probability Phe₁(t) = P(X₁ = E₁|X0 = H) of moving from a healthy
state to the event of interest.
iii. Find the expected remaining lifetime of a healthy subject.
=
(b) From the observations of sample paths of Markov chain X {X, t≥ 0} with state space
S = {1,2,3}, the number of transitions Nij between states i, j = S and the length of time
Z; spent in each state i = S are reported in the matrices below
0 20 30
10
N = 40 0 50
10 20 0
Z =
20
5
Elements qij of the intensity matrix Q is found as the maximizer of likelihood function
3 3
L({ij}) = [[((ij)
i=1 j#i
i. Find the estimate 7i; of the intensity qij.
ii. Use the given observations to find an estimate of the intensity matrix Q.
Transcribed Image Text:2. (a) A Markov chain X = {X, 0} is used for a competing risk analysis based on the following simple diagram with the respective transition rates H E1 7 5 E2 Figure 1: Transition diagram of a simple competing risk model. where H represents a healthy state, E₁ event of interest, and E2 other type of exit. i. Write down the intensity matrix of the Markov chain. ii. Find the transition probability Phe₁(t) = P(X₁ = E₁|X0 = H) of moving from a healthy state to the event of interest. iii. Find the expected remaining lifetime of a healthy subject. = (b) From the observations of sample paths of Markov chain X {X, t≥ 0} with state space S = {1,2,3}, the number of transitions Nij between states i, j = S and the length of time Z; spent in each state i = S are reported in the matrices below 0 20 30 10 N = 40 0 50 10 20 0 Z = 20 5 Elements qij of the intensity matrix Q is found as the maximizer of likelihood function 3 3 L({ij}) = [[((ij) i=1 j#i i. Find the estimate 7i; of the intensity qij. ii. Use the given observations to find an estimate of the intensity matrix Q.
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