#2 and #4

Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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#2 and #4

QUESTION 1
Consider the 2-step synthesis problem shown below to answer questions 1-4.
HO
Reagent
Reagent
2
OH
Intermediate
Product
Br
Number the carbons in your starting material. Identify the corresponding carbons in your product and number them accordingly. A new C-C bond was made. Click on that new C-C bond in the image of the final product shown below.
HO
Selected Coordinates
Clear
QUESTION 2
Think retrosynthetically. Consider the bonding patterns and connectivity in your product. What type of electrophile was paired with the organometallic reagent that was used to form the new C-C bond?
O A Aldehyde
O B. Alkyl bromide
O C. Ketone
O D. Epoxide
QUESTION 3
Think retrosynthetically. Consider the bonding patterns and connectivity in your product and the new piece that was added. Which organometallic reagent was used to form the new C-C bond?
A)
OH
B)
MgBr
D)
C) MgBr
MgBr
MgBr
O A
B
C
O D
QUESTION 4
Based on your previous retrosynthetic analysis, you should determine the structure of the Intermediate Product and whether you need to convert your starting material into the organometallic nucleophile or the electrophile.
Compare the structure of your starting material to the structure of the Intermediate Product. What is Reagent 1?
O A NaH
О В. СIMS, рyridine
O C. H2SO4, heat
O D. Cro3, H20, H2SO4
Transcribed Image Text:QUESTION 1 Consider the 2-step synthesis problem shown below to answer questions 1-4. HO Reagent Reagent 2 OH Intermediate Product Br Number the carbons in your starting material. Identify the corresponding carbons in your product and number them accordingly. A new C-C bond was made. Click on that new C-C bond in the image of the final product shown below. HO Selected Coordinates Clear QUESTION 2 Think retrosynthetically. Consider the bonding patterns and connectivity in your product. What type of electrophile was paired with the organometallic reagent that was used to form the new C-C bond? O A Aldehyde O B. Alkyl bromide O C. Ketone O D. Epoxide QUESTION 3 Think retrosynthetically. Consider the bonding patterns and connectivity in your product and the new piece that was added. Which organometallic reagent was used to form the new C-C bond? A) OH B) MgBr D) C) MgBr MgBr MgBr O A B C O D QUESTION 4 Based on your previous retrosynthetic analysis, you should determine the structure of the Intermediate Product and whether you need to convert your starting material into the organometallic nucleophile or the electrophile. Compare the structure of your starting material to the structure of the Intermediate Product. What is Reagent 1? O A NaH О В. СIMS, рyridine O C. H2SO4, heat O D. Cro3, H20, H2SO4
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