2 (a) Allylation is a powerful way to make compounds such as 8 and 9 diastereoselectively.OHонallylationPhorPhPh89(i) Allyl Grignard reagents [RCH=CHCH,MgBr] cannot be used to make 8 and 9 selectively. Withthe aid of a diagram explain why.(ii) Which isomer of the allyl boronate 10 would you require to synthesise 8 selectively? Drawand provide comments on the transition state of the allylation reaction of 10 withbenzaldehyde to support your answer.B-O10

As per the rule, only the first question can be answered.

2 (a) Allylation is a powerful way to make compounds such as 8 and 9 diastereoselectively. он OH allylation Ph or Ph Ph H. (i) Allyl Grignard reagents [RCH=CHCH,MgBr] cannot be used to make 8 and 9 selectively. With the aid of a diagram explain why.

2 (a) Allylation is a powerful way to make compounds such as 8 and 9 diastereoselectively. он OH allylation Ph or Ph Ph H. (i) Allyl Grignard reagents [RCH=CHCH,MgBr] cannot be used to make 8 and 9 selectively. With the aid of a diagram explain why.

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Diol

In chemistry there are so many chemical compounds that have a hydroxyl group but a chemical compound having two hydroxyl groups (-OH) is termed as a diol. It also implies the presence of two alcohols whereas polyols contain two or more than two hydroxyl groups (-OH). Glycol or 1,2-diol is an aliphatic diol that has two alcohol groups on adjacent carbon atoms. In industries, the most commonly used diol is ethylene glycol.

Question

2 (a) Allylation is a powerful way to make compounds such as 8 and 9 diastereoselectively.
OH
он
allylation
Ph
or
Ph
Ph
8
9
(i) Allyl Grignard reagents [RCH=CHCH,MgBr] cannot be used to make 8 and 9 selectively. With
the aid of a diagram explain why.
(ii) Which isomer of the allyl boronate 10 would you require to synthesise 8 selectively? Draw
and provide comments on the transition state of the allylation reaction of 10 with
benzaldehyde to support your answer.
B-O
10

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