13. Reflect and Apply Aspirin is an acid with a pK, of 3.5; its structure includes a carboxyl group. To be absorbed into the bloodstream, it must pass through the membrane lining the stomach and the small intestine. Electrically neutral molecules can pass through a mem- brane more easily than can charged molecules. Would you expect more aspirin to be absorbed in the stomach, where the pH of gas- tric juice is about 1, or in the small intestine, where the pH is about 6? Explain your answer.
13. Reflect and Apply Aspirin is an acid with a pK, of 3.5; its structure includes a carboxyl group. To be absorbed into the bloodstream, it must pass through the membrane lining the stomach and the small intestine. Electrically neutral molecules can pass through a mem- brane more easily than can charged molecules. Would you expect more aspirin to be absorbed in the stomach, where the pH of gas- tric juice is about 1, or in the small intestine, where the pH is about 6? Explain your answer.
Biochemistry
9th Edition
ISBN:9781305961135
Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Chapter2: Water: The Solvent For Biochemical Reactions
Section: Chapter Questions
Problem 21RE: REFLECT AND APPLY Aspirin is an acid with a pKa of 3.5; its structure includes a carboxyl group. To...
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![13. Reflect and Apply Aspirin is an acid with a pK, of 3.5; its structure
includes a carboxyl group. To be absorbed into the bloodstream, it
must pass through the membrane lining the stomach and the small
intestine. Electrically neutral molecules can pass through a mem-
brane more easily than can charged molecules. Would you expect
more aspirin to be absorbed in the stomach, where the pH of gas-
tric juice is about 1, or in the small intestine, where the pH is about
6? Explain your answer.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F668fa022-afb3-4810-bb4a-84a892434255%2Fc34b29df-f0a9-4b95-821e-fb62426e38d6%2Fvqf5f9h_processed.jpeg&w=3840&q=75)
Transcribed Image Text:13. Reflect and Apply Aspirin is an acid with a pK, of 3.5; its structure
includes a carboxyl group. To be absorbed into the bloodstream, it
must pass through the membrane lining the stomach and the small
intestine. Electrically neutral molecules can pass through a mem-
brane more easily than can charged molecules. Would you expect
more aspirin to be absorbed in the stomach, where the pH of gas-
tric juice is about 1, or in the small intestine, where the pH is about
6? Explain your answer.
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