111 The disease is caused by single amino acid mutation in the beta globin chain of hemoglobin and causes the protein to aggregate. 11J Resting individuals have high ATP concentrations in their mitochondrial matrix. How would you expect elevated ATP levels to effect the concentrations of the following metabolites? i) NADH ii) ADP iii) Citrate increase // decrease increase // decrease increase // decrease

Principles Of Pharmacology Med Assist
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ISBN:9781337512442
Author:RICE
Publisher:RICE
Chapter25: Diuretics And Medications Used For Urinary System Disorders
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Please help with parts I and J.

### Biology Examination Questions

**11I** The disease __________________ is caused by a single amino acid mutation in the beta-globin chain of hemoglobin and causes the protein to aggregate.

**11J** Resting individuals have high ATP concentrations in their mitochondrial matrix. How would you expect elevated ATP levels to affect the concentrations of the following metabolites?

i) NADH  -  increase // decrease  
ii) ADP  -  increase // decrease  
iii) Citrate  -  increase // decrease
Transcribed Image Text:### Biology Examination Questions **11I** The disease __________________ is caused by a single amino acid mutation in the beta-globin chain of hemoglobin and causes the protein to aggregate. **11J** Resting individuals have high ATP concentrations in their mitochondrial matrix. How would you expect elevated ATP levels to affect the concentrations of the following metabolites? i) NADH - increase // decrease ii) ADP - increase // decrease iii) Citrate - increase // decrease
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