11.49 What is the best-fitting regression line relating mean thyroxine level to gestational age? Hint: 10 10 10 Σx = 285, Σx = 8205, Σy = 78.4 i=1 i=1 i=1 10 Σy = 627.88, i=1 10 Σxiyi = 2264.7 i=1

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Pediatrics, Endocrinology
Transient hypothyroxinemia, a common finding in premature
infants, is not thought to have long-term consequences or
to require treatment. A study was performed to investigate
whether hypothyroxinemia in premature infants is a cause of
subsequent motor and cognitive abnormalities [16]. Blood
thyroxine values were obtained on routine screening in the
first week of life from 536 infants who weighed 2000 g or
less at birth and were born at 33 weeks gestation or earlier.
The data in Table 11.21 were presented concerning the
relationship between mean thyroxine level and gestational
age.
11.49 What is the best-fitting regression line relating mean
thyroxine level to gestational age?
Hint:
10
10
10
Σx = 285, Σx = 8205, Σy; = 78.4
i=1
i=1
i=1
10
Σy = 627.88,
i=1
10
Σxy; = 2264.7
i=1
Transcribed Image Text:Pediatrics, Endocrinology Transient hypothyroxinemia, a common finding in premature infants, is not thought to have long-term consequences or to require treatment. A study was performed to investigate whether hypothyroxinemia in premature infants is a cause of subsequent motor and cognitive abnormalities [16]. Blood thyroxine values were obtained on routine screening in the first week of life from 536 infants who weighed 2000 g or less at birth and were born at 33 weeks gestation or earlier. The data in Table 11.21 were presented concerning the relationship between mean thyroxine level and gestational age. 11.49 What is the best-fitting regression line relating mean thyroxine level to gestational age? Hint: 10 10 10 Σx = 285, Σx = 8205, Σy; = 78.4 i=1 i=1 i=1 10 Σy = 627.88, i=1 10 Σxy; = 2264.7 i=1
TABLE 11.21 Relationship between mean
(x)
Gestational age
(weeks)
≤24ª
25
26
27
28
29
30
31
32
33
thyroxine level and gestational age
among 536 premature infants
(y)
Mean thyroxine level
(µg/dL)
6.5
7.1
7.0
7.1
7.2
7.1
8.1
8.7
9.5
10.1
aTreated as 24 in subsequent analyses.
11.50 Is there a significant association between mean thy-
roxine level and gestational age? Report a p-value.
Transcribed Image Text:TABLE 11.21 Relationship between mean (x) Gestational age (weeks) ≤24ª 25 26 27 28 29 30 31 32 33 thyroxine level and gestational age among 536 premature infants (y) Mean thyroxine level (µg/dL) 6.5 7.1 7.0 7.1 7.2 7.1 8.1 8.7 9.5 10.1 aTreated as 24 in subsequent analyses. 11.50 Is there a significant association between mean thy- roxine level and gestational age? Report a p-value.
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