10 9 12 11 CHEM3312 GW-2B 3 PBr3 1) BH3, THF 2)H₂O2, NaOH, H₂O CH₂OH, H+ CH₂OH major NaOEt heat 8 6 HBr, peroxide 5 2 1 NBS minor *epoxydation CH3MgBr H₂SO4 heat Cl₂, H₂O NaOMe heat major D₂, Pd-C 7 26 27 CI ↓ NaCN H3O+ 15 14 NaSCH3 NaOH DMSO (SN) SOCI₂ 25 13 28 TSCI 17 (CH₂)₂CULI 24 PCC CH3CH,NH, H+ (CH3)2NH H+ CH₂OH 29 30 18 16 NaBH₁ 23 H+ HO(CH₂)₂OH CH₂MgBr DIBAH HCN 19 1) LDA 2) CH₂Br NaOMe NaOH 22 31 21 20 or (Aldol condensation) (Claisen condensation)
Reactions of Alkyl and Aryl halides
In organic chemistry, an alkyl halide is formed when an atom of hydrogen is switched by a halogen in a hydrocarbon or aliphatic compound. An aryl halide is formed when an atom of hydrogen is substituted by a halogen atom in an aromatic compound. Metals react with aryl halides and alkyl halides and they also go through nucleophilic substitution reactions and elimination reactions.
Zaitsev's Rule in Organic Chemistry
Alexander Zaitsev (also pronounced as Saytzeff), in 1875, prepared a rule to help predict the result of elimination reactions which stated, "The favored product in dehydrohalogenation reactions is that alkene that has the majority of alkyl groups attached to the double-bonded carbon atoms."
Tosylate
Tosylates are important functional groups in organic chemistry, mainly because of two important properties which they possess:
Alkyl Halides
A functional group is a collection of several atoms or bonds with certain characteristic chemical properties and reactions associated with it. There is a presence of a halogen atom (F, Cl, Br, or I; it represents any halogen atom), as a functional group in alkyl halides. Therefore, it can be said that alkanes that contain a halogen compound are called alkyl halides.
Step by step
Solved in 5 steps with 3 images
