1. You have identified a novel protein that shows structural similarity with NELF. You next examined transcription using HeLa nuclear extracts. While endogenous NELF can repress transcription, your novel protein reversed this inhibition. (a) Based on the given information, please propose a mechanism for your novel protein. (b) Design an experiment to test your hypothesis.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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1. You have identified a novel protein that
shows structural similarity with NELF. You next
examined transcription using Hela nuclear
extracts. While endogenous NELF can repress
transcription, your novel protein reversed this
inhibition. (a) Based on the given information,
please propose a mechanism for your novel
protein. (b) Design an experiment to test your
hypothesis.
Transcribed Image Text:1. You have identified a novel protein that shows structural similarity with NELF. You next examined transcription using Hela nuclear extracts. While endogenous NELF can repress transcription, your novel protein reversed this inhibition. (a) Based on the given information, please propose a mechanism for your novel protein. (b) Design an experiment to test your hypothesis.
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