Show steps pls 1. The half-life of perfluorooctanoic acid (PFOA) in female humans isapproximately 3.8 years. If the concentration in the adipose tissue of awoman is 136 ng/g, how long would it take for the level to drop to 10ng/g (assuming no further exposure occurs).2. A drug appears to follow first-order elimination kinetics. If theplasma concentration following complete absorption of an oral dose is65 µg/L and 4 hours later it is 25 µg/L, calculate the elimination half-life of the drug.3. Plasma concentrations following a dose of a drug are shown below.Calculate the elimination rate constant for the agent based on thesedata. (Hint: create a plot using Excel and see if you can determine avalue for a slope.)time (hours) concentration (ng/ml)1662755847362720158.54.52.50.51234681012162024

Answered: 1. The half-life of perfluorooctanoic…

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Show steps pls

1. The half-life of perfluorooctanoic acid (PFOA) in female humans is
approximately 3.8 years. If the concentration in the adipose tissue of a
woman is 136 ng/g, how long would it take for the level to drop to 10
ng/g (assuming no further exposure occurs).
2. A drug appears to follow first-order elimination kinetics. If the
plasma concentration following complete absorption of an oral dose is
65 µg/L and 4 hours later it is 25 µg/L, calculate the elimination half-
life of the drug.
3. Plasma concentrations following a dose of a drug are shown below.
Calculate the elimination rate constant for the agent based on these
data. (Hint: create a plot using Excel and see if you can determine a
value for a slope.)
time (hours) concentration (ng/ml)
16
62
75
58
47
36
27
20
15
8.5
4.5
2.5
0.5
1
2
3
4
6
8
10
12
16
20
24

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