1. Rank the alanes below in order of increasing relative Lewis acidity (1 is most acidic, 4 is least acidic). Provide a brief explanation for your ordering. AlCl3 Al(Et)3 Rank: AICI(Et)2 AlCl2(Et)

please write clearly!

27(c) Most basic nitrogen A or B? (Hint: The lone pairs on the two play different roles in the aromaticity of the molecule, and consequently one Nitrogen will get protonated before the other)

Treatment of indene with NaNH2 forms its conjugate base in a Brønsted–Lowry acid–base reaction. Draw all reasonable resonance structures forindene's conjugate base, and explain why the pKa of indene is lower thanthe pKa of most hydrocarbons.

Dd.22.

As far back as the 16th century, South American Incas chewed the leaves of the coca bush, Erythroxylon coca, to combat fatigue. Chemical studies of Erythroxylon coca by Friedrich Wöhler in 1862 resulted in the discovery of cocaine, C17H21NO4, as the active component. Basic hydrolysis of cocaine leads to methanol, benzoic acid, and another compound called ecgonine, C9H15NO3. Oxidation of ecgonine with CrO3 yields a keto acid that readily loses CO2 on heating, giving tropinone. (a) What is a likely structure for the keto acid? (b) What is a likely structure for ecgonine, neglecting stereochemistry? (c) What is a likely structure for cocaine, neglecting stereochemistry?

The pKa, of the conjugate acid of morpholine is 8.33. (a) Calculate the ratio of morpholine to morpholinium ion in aqueous solution at pH 7.0. (b) At what pH are the concentrations of morpholine and morpholinium ion equal?

The gas-phase basicity of triphenylamine (876.4 kJ mol-1) is less thanthat of triphenylphosphine (940.4 kJ mol-1). Write an equation torepresent each reaction. Do you expect electronic or steric factors tocontribute more to this difference? Explain

3. Rationalize the substantial differences in relative rates of alkaline hydrolysis for the following pair of amides: Ph N7 105 > Ph NH₂

22. Which of the following is FALSE with regard to acid strength? A) B) C) D) E) HCIO3 > HCIO₂ H₂SO3 > H3PO3 HBr > H₂S H₂O > NH3 HF > HI