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1. On October 22, 2020, the FDA approved Veklury (remdesivir structure shown below) for use in adults and pediatric patients for the treatment of COVID-19 requiring hospitalization. A) Calculate the Kier-Hall electronegativity index (x) of atoms a-c. H₂C H₂C CH3 H HO OH NH₂ 2 a (N) b (P) c (0) : = = 2 3 4 5 IV C V VI VII N O F P S CI Bri 1

1. On October 22, 2020, the FDA approved Veklury (remdesivir structure shown below) for use in adults and pediatric patients for the treatment of COVID-19 requiring hospitalization. A) Calculate the Kier-Hall electronegativity index (x) of atoms a-c. H₂C H₂C CH3 H HO OH NH₂ 2 a (N) b (P) c (0) : = = 2 3 4 5 IV C V VI VII N O F P S CI Bri 1

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
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Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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1. On October 22, 2020, the FDA approved Veklury (remdesivir structure shown below) for use in adults and pediatric patients for the treatment of COVID-19 requiring hospitalization. A) Calculate the Kier-Hall electronegativity index (x) of atoms a-c. H₂C. H₂C CH3 N P H d (CN) TAKE A TOUR NH₂ CEN НО ОН 3 a (N) = b (P) = c (0) = 2 3 4 5 IV с V N P C) Calculate the Kier-Hall electronegativity index (x) for functional group d. Show your calculations. VI VII O F B) Using the information from A (above), denote the most polar bond in remdesivir by drawing its molecular dipole (use correct convention). S CI Br 1
Transcribed Image Text:1. On October 22, 2020, the FDA approved Veklury (remdesivir structure shown below) for use in adults and pediatric patients for the treatment of COVID-19 requiring hospitalization. A) Calculate the Kier-Hall electronegativity index (x) of atoms a-c. H₂C. H₂C CH3 N P H d (CN) TAKE A TOUR NH₂ CEN НО ОН 3 a (N) = b (P) = c (0) = 2 3 4 5 IV с V N P C) Calculate the Kier-Hall electronegativity index (x) for functional group d. Show your calculations. VI VII O F B) Using the information from A (above), denote the most polar bond in remdesivir by drawing its molecular dipole (use correct convention). S CI Br 1
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