1. In rabbits, coloration of the fur depends on alleles of the gene c. From information given in the chapter, what phenotypes and proportions would be expected from the following crosses: a) CC X cc b) ccx cc c) Cc x Cech d) cc x cc

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**Additional Problems (Chapter 4: Extension of Mendelian Inheritance):**

1. **In rabbits, coloration of the fur depends on alleles of the gene C. From information given in the chapter, what phenotypes and proportions would be expected from the following crosses:**

   a) CC x cc  
   b) Cc x Cc  
   c) Ccᶜʰ x Ccᶜʰ  
   d) ccᶜʰ x cc  

2. **From the information given in the chapter about the ABO blood types, what phenotypes and ratios are expected from the following matings:**

   a) Type AB x type O  
   b) Type AB x type B individual whose mother is type O  
   c) Type O x Type A individual whose father is type O  
   d) Type O x type O  

3. **A woman with type AB blood type gave birth to a baby with type B blood. Two different men claim to be the father. One has type A blood and the other type B blood. Can the genetic evidence decide in favor of either?**

4. **You have been studying a trait that seems to be present in every generation within a particular family. Further, you have observed that every affected offspring has at least one affected parent in any particular generation.**

   a) This trait is more likely due to a dominant or recessive allele?  
   b) Interestingly, this allele is completely penetrant in the homozygous state while only 75% penetrant in the heterozygous condition. If two heterozygous individuals who carry this allele are mated, what is the expected proportion of affected progeny?  

5. **A man who is not bald married a non-bald female whose mother is bald.**

   A. What is the chance that the couple will have a bald son?  
   B. What is the probability that the couple will have a bald daughter?  
   C. What is the chance that the couple will have a nonbald daughter?
Transcribed Image Text:**Additional Problems (Chapter 4: Extension of Mendelian Inheritance):** 1. **In rabbits, coloration of the fur depends on alleles of the gene C. From information given in the chapter, what phenotypes and proportions would be expected from the following crosses:** a) CC x cc b) Cc x Cc c) Ccᶜʰ x Ccᶜʰ d) ccᶜʰ x cc 2. **From the information given in the chapter about the ABO blood types, what phenotypes and ratios are expected from the following matings:** a) Type AB x type O b) Type AB x type B individual whose mother is type O c) Type O x Type A individual whose father is type O d) Type O x type O 3. **A woman with type AB blood type gave birth to a baby with type B blood. Two different men claim to be the father. One has type A blood and the other type B blood. Can the genetic evidence decide in favor of either?** 4. **You have been studying a trait that seems to be present in every generation within a particular family. Further, you have observed that every affected offspring has at least one affected parent in any particular generation.** a) This trait is more likely due to a dominant or recessive allele? b) Interestingly, this allele is completely penetrant in the homozygous state while only 75% penetrant in the heterozygous condition. If two heterozygous individuals who carry this allele are mated, what is the expected proportion of affected progeny? 5. **A man who is not bald married a non-bald female whose mother is bald.** A. What is the chance that the couple will have a bald son? B. What is the probability that the couple will have a bald daughter? C. What is the chance that the couple will have a nonbald daughter?
## Genetics Problem Set

### Question 6
A man with X-linked colorblindness marries a woman with no history of colorblindness in her family. Their daughter marries a normal man and they have one daughter. This couple also has one child with colorblindness. 

**Questions:**
A. What is the chance that the next child will be colorblind?
B. What is the chance that this last couple will have an affected daughter?

---

### Question 7
Two strains of mice are homozygous for a recessive mutation causing small eyes. Both mutations appear indistinguishable. One mutation is termed "little eye," and the other "tiny eye." How can you determine if these mutations are alleles of the same gene?

---

### Question 8
An insect strain with white eyes (genotype RRww) is crossed with a strain having cream eyes (genotype rrWw). All F1 offspring have red eyes. Upon interbreeding the F1 generation, the F2 generation consists of 175 red-eyed, 62 cream-eyed, and 81 white-eyed individuals.

**Tasks:**
i. Describe the genetics of this trait.
ii. Provide genotypes for the F1 and F2 generations.

---

### Question 9
In wild sunflowers, there are populations with either yellow or white flowers. A true-breeding white variety is crossed with a pure strain of white-flowered plants. The F1 progeny have yellow flowers. Interbreeding the F1 plants yields 56 yellow and 44 white-flowered offspring. 

**Questions:**
- How many genes control flower color?
- Is there any epistasis between the genes?

**Note:** There is a hand-drawn diagram at the bottom of the document indicating a genetic pathway labeled "white → cream → red."
Transcribed Image Text:## Genetics Problem Set ### Question 6 A man with X-linked colorblindness marries a woman with no history of colorblindness in her family. Their daughter marries a normal man and they have one daughter. This couple also has one child with colorblindness. **Questions:** A. What is the chance that the next child will be colorblind? B. What is the chance that this last couple will have an affected daughter? --- ### Question 7 Two strains of mice are homozygous for a recessive mutation causing small eyes. Both mutations appear indistinguishable. One mutation is termed "little eye," and the other "tiny eye." How can you determine if these mutations are alleles of the same gene? --- ### Question 8 An insect strain with white eyes (genotype RRww) is crossed with a strain having cream eyes (genotype rrWw). All F1 offspring have red eyes. Upon interbreeding the F1 generation, the F2 generation consists of 175 red-eyed, 62 cream-eyed, and 81 white-eyed individuals. **Tasks:** i. Describe the genetics of this trait. ii. Provide genotypes for the F1 and F2 generations. --- ### Question 9 In wild sunflowers, there are populations with either yellow or white flowers. A true-breeding white variety is crossed with a pure strain of white-flowered plants. The F1 progeny have yellow flowers. Interbreeding the F1 plants yields 56 yellow and 44 white-flowered offspring. **Questions:** - How many genes control flower color? - Is there any epistasis between the genes? **Note:** There is a hand-drawn diagram at the bottom of the document indicating a genetic pathway labeled "white → cream → red."
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