1. Acetyl-CoA labeled with 14C in both of its acetatecarbon atoms is incubated with unlabeled oxaloacetatand a crude tissue preparation capable of carrying outthe reactions of the citric acid cycle. After one turn ofthe cycle, oxaloacetate would have ¹4C in:A. all four carbon atoms.B.no pattern that is predictable from the informationprovided.c.none of its carbon atoms.D.the keto carbon and one of the carboxyl carbons.E. the two carboxyl carbons.

The citric acid cycle, also called as the Tricarboxylic acid (TCA) cycle is the central metabolic…

Answered: 1. Acetyl-CoA labeled with ¹4C in both…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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1.3. Aerobic Cellular Respiration: a.Write the chemical formula for the aerobic cellular respiration of glucose. b. List the major steps of aerobic cellular respiration and describe the major events of each step.c. Explain the role of an electron carrier in cellular respiration.d. Predict what would happen to the process of cellular respiration if oxygen was not present. In your answer, specifically state the role that oxygen plays in cellular respiration.
Gluconeogensis uses nearly all of the same enzymes as those in ____, and is a(an) ______ reaction. Select one: a. Citric Acid Cycle anabolic b. citric acid cycle, catabolic c. glycolysis, anabolic d. glycolysis, catabolic e. none of the above
1.a. Given what you know about glycolysis and gluconeogenesis, does it make sense that insulin activates PDH phosphatase? Why? b.How do vitamins increase to the breadth of chemical reactions available within a biological system?
Which of the following molecules shown are the reduced products produced in the citric acid cycle whose reduction directly helped drive oxidation? Select all that apply. Ensure you are selecting the product forms of the molecule, which here means the reduced form, and are only considering redox reactions! Do not include the pyruvate processing steps -- just the citric acid cycle itself. A. GDP B. NADH C. FAD D. Acetyl-CoA E. NAD+ F. CoA G. FADH2 H. GTP I. QH2 J. Q
Consider the following types of cell and their respective conditions: i. a liver cell with non-functional malate-aspartate shuttle* ii. a skeletal muscle cell lacking oxygen iii. a cell with ATP synthase deficiency* iv. a yeast cell undergoing fermentation but with defective alcohol dehydrogenase (hint: In yeast, alcohol dehydrogenase is responsible for shuttling reducing equivalents of cytosolic NADH to the mitochondria.)* V. a brain cell with non-functional Complex II of the electron transport chain* * Assume that the deficiency is isolated and will not influence the function of other respiration components
9. The equation below depicts the first step of the citric acid cycle. H0 CoA-SH CH-C + 0=C-CO0 HO C-COO citrate s-COA ČH2-COO synthase ČH2 -CO0 Citrate Acetyl-CoA Oxaloacetate AG" = -32.2 kJ/mol a) Explain the chemical conversions that take place during this step. b) Why is this reaction energetically favorable? Explain.
Fatty acids are catabolized by a process called beta-oxidation. One of the products of beta- oxidation is acetyl CoA. Given this information, the products of beta-oxidation will most likely be incorporated into which stage of cellular respiration? A the citric acid cycle B C D glycolysis oxidative phosphorylation the link reaction
[References) Which of the following statements explains why acetyl-CoA Iis considered the central molecule of metabolism? (Select all that apply.) O The addition of acetyl-CoA to compounds stabilises them. Acetyl-CoA contains a thioester bond that makes it one of the high energy compounds in metabolic pathways. O Acetyl-CoA is an inhibitor that plays a central role in regulating metabolic pathways. O Acetyl-CoA feeds directly into the citric acid cycle. U None of the above.
In Yeast, pyruvate can be directly converted into: A. acetyl-CoA and ethanol B. acetyl-CoA only C. lactate only D. ethanol only
b and e are wrong, please give the correct answer and explan

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