1) R2NH, H,-H2O B. Cycloheptanone 2) ETHC=CHCOEt 3) H30*

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### Topic: Reactions Involving Cycloheptanone and Ethyl Nitroacetate

#### B. Cycloheptanone Reactions
The following steps outline a series of chemical reactions starting with cycloheptanone:

1. **Reagents**: \(R_2NH\), \(H^+\), and \(- H_2O\)
2. **Reagent**: \(EtHC=CHCOOEt\)
3. **Reagent**: \(H_3O^+\)

#### C. Ethyl Nitroacetate (EtCOCH\(_2\)NO\(_2\)) Reactions
The following steps outline a series of chemical reactions starting with ethyl nitroacetate:

1. **Reagent**: \(KOH\)
2. **Reagent**: \(PhHC=CHCOOMe\)
3. **Reagent**: \(H_3O^+\)

### Detailed Explanation
1. **Reagent 1 in Reaction B:** The first step involves cycloheptanone reacting with a secondary amine (\(R_2NH\)), in the presence of an acidic medium (H\(^+\)), with the concurrent removal of water (- H\(_2\)O).
  
2. **Reagent 2 in Reaction B:** This is followed by a reaction with ethyl (E)-2-cyclohepten-1-one carboxylate (EtHC=CHCOOEt).

3. **Reagent 3 in Reaction B:** The final step involves hydrolysis using hydronium ions (H\(_3\)O^+).

4. **Reagent 1 in Reaction C:** Ethyl nitroacetate (EtCOCH\(_2\)NO\(_2\)) reacts with potassium hydroxide (KOH).

5. **Reagent 2 in Reaction C:** This is followed by a reaction with methyl cinnamate (PhHC=CHCOOMe).

6. **Reagent 3 in Reaction C:** The final step involves hydrolysis using hydronium ions (H\(_3\)O^+). 

These reaction sequences demonstrate specific transformations involving cycloheptanone and ethyl nitroacetate, showing the utility of various organic reagents and reaction conditions in advancing chemical synthesis.
Transcribed Image Text:### Topic: Reactions Involving Cycloheptanone and Ethyl Nitroacetate #### B. Cycloheptanone Reactions The following steps outline a series of chemical reactions starting with cycloheptanone: 1. **Reagents**: \(R_2NH\), \(H^+\), and \(- H_2O\) 2. **Reagent**: \(EtHC=CHCOOEt\) 3. **Reagent**: \(H_3O^+\) #### C. Ethyl Nitroacetate (EtCOCH\(_2\)NO\(_2\)) Reactions The following steps outline a series of chemical reactions starting with ethyl nitroacetate: 1. **Reagent**: \(KOH\) 2. **Reagent**: \(PhHC=CHCOOMe\) 3. **Reagent**: \(H_3O^+\) ### Detailed Explanation 1. **Reagent 1 in Reaction B:** The first step involves cycloheptanone reacting with a secondary amine (\(R_2NH\)), in the presence of an acidic medium (H\(^+\)), with the concurrent removal of water (- H\(_2\)O). 2. **Reagent 2 in Reaction B:** This is followed by a reaction with ethyl (E)-2-cyclohepten-1-one carboxylate (EtHC=CHCOOEt). 3. **Reagent 3 in Reaction B:** The final step involves hydrolysis using hydronium ions (H\(_3\)O^+). 4. **Reagent 1 in Reaction C:** Ethyl nitroacetate (EtCOCH\(_2\)NO\(_2\)) reacts with potassium hydroxide (KOH). 5. **Reagent 2 in Reaction C:** This is followed by a reaction with methyl cinnamate (PhHC=CHCOOMe). 6. **Reagent 3 in Reaction C:** The final step involves hydrolysis using hydronium ions (H\(_3\)O^+). These reaction sequences demonstrate specific transformations involving cycloheptanone and ethyl nitroacetate, showing the utility of various organic reagents and reaction conditions in advancing chemical synthesis.
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