1) From the Acids/Bases Handout: Given this tetrapeptide: 9.67(b) Cysteine Glutamic acid Alanine SH 254 H₂N 4.25 (a) Glutamic acid OH Turn it into a cartoon and fill in the pKas from the table. With the pKas note whether they are acidic (a) or basic (b). And, if it's a non-ionizable side group (like alanine) let's just put an R. Lysine 8.18 (a) Cysteine NH₂ R Alanine OH 10.53 (b) Lysine 2.18(a) a) Starting from an extremely low pH (1) and moving to an extremely high pH (13) show the changing charges by writing the charges in the boxes (+,-, 0). Identify each pKa responsible for a change in predominant net charge (as done in lecture). b) Based on your answer to a, what is the pl of this tetrapeptide? c) At pH=9.0, would this tetrapeptide move toward a positive electrode or a negative electrode? (In other words, would it carry a net positive or a net negative charge?)
Neutral Amino Acids
Amino acids which do not have any charge on them are neutral amino acids.
Globular Protein
The globular proteins refer to the shape of protein specifically spherical in nature apart from spherical form fibrous, disordered and membrane-bound proteins exist. These globular proteins are miscible in water and form a colloidal solution rather than other types which might not exhibit solubility. Many classes of the fold are found in globular proteins, which render them a sphere shape. Globular fold containing proteins usually are referred to by the term globin.
Dimer
Dimers are basic organic compounds, which are derivates of oligomers. It is formed by the combination of two monomers which could potentially be strong or weak and in most cases covalent or intermolecular in nature. Identical monomers are called homodimer, the non-identical dimers are called heterodimer. The method by which dimers are formed is known as “dimerization”.
Dipeptide
A dipeptide is considered a mixture of two distinct amino acids. Since the amino acids are distinct, based on their composition, two dipeptide's isomers can be produced. Various dipeptides are biologically essential and are therefore crucial to industry.
can you help me with question a and b please
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