Chromium supplements usually contain 200 ug of chromium in the form.of the bright red chromium picolinate, shown below. The supplementsare promoted as a treatment for type 2 diabetes and as an aid to weightloss, although neither use has been confirmed in clinical studies. Thiscan be determined using capillary electrophoresis. The peak areas of aseries of standards resulted in the following data.[C]/ ugL-10.50100150200250Peak Area0.1210.2350.3610.4790.604These data were plotted to provide a calibration curve for the analysis ofvitamin supplements containing unknown quantities of chromium, andthe best fit line was determined to be:y 0.00241 x - 0.0014with a correlation factor, r, of 0.9984. The analysis of chromium in thesupplement was conducted five times with each tablet being dissolved inThe resultant solutions100 ml of water, sonicated and filtered.underwent a 10 fold dilution (1 ml in 10 ml total) prior to theThe peak areas obtained for each sample were asmeasurement.follows; 0.457,0.465, 0.439, 0.442 and 0.448.(1) Calculate the concentration (ugL-1) of chromium in the solution.(1) Calculate the amount (ug) of chromium in the original tablets.(iii) The manufacturing specification was 200 + 7.5 pg of chromium.Calculate whether the tablet concentration complies withspecification or not.this

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(1) Calculate the concentration (ugL-1) of chromium in the solution. (ii) Calculate the amount (ug) of chromium in the original tablets. (ii) The manufacturing specification was 200 t 7.5 pg of chromium. Calculate whether the tablet concentration complies with this specification or not.

(1) Calculate the concentration (ugL-1) of chromium in the solution. (ii) Calculate the amount (ug) of chromium in the original tablets. (ii) The manufacturing specification was 200 t 7.5 pg of chromium. Calculate whether the tablet concentration complies with this specification or not.

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

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Question

Chromium supplements usually contain 200 ug of chromium in the form.
of the bright red chromium picolinate, shown below. The supplements
are promoted as a treatment for type 2 diabetes and as an aid to weight
loss, although neither use has been confirmed in clinical studies. This
can be determined using capillary electrophoresis. The peak areas of a
series of standards resulted in the following data.
[C]/ ugL-1
0.
50
100
150
200
250
Peak Area
0.121
0.235
0.361
0.479
0.604
These data were plotted to provide a calibration curve for the analysis of
vitamin supplements containing unknown quantities of chromium, and
the best fit line was determined to be:
y 0.00241 x - 0.0014
with a correlation factor, r, of 0.9984. The analysis of chromium in the
supplement was conducted five times with each tablet being dissolved in
The resultant solutions
100 ml of water, sonicated and filtered.
underwent a 10 fold dilution (1 ml in 10 ml total) prior to the
The peak areas obtained for each sample were as
measurement.
follows; 0.457,0.465, 0.439, 0.442 and 0.448.
(1) Calculate the concentration (ugL-1) of chromium in the solution.
(1) Calculate the amount (ug) of chromium in the original tablets.
(iii) The manufacturing specification was 200 + 7.5 pg of chromium.
Calculate whether the tablet concentration complies with
specification or not.
this

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