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01110 0= -P-OCH₂ 51 5 HN 6 OH 3. CH₂

01110 0= -P-OCH₂ 51 5 HN 6 OH 3. CH₂

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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The image shows the chemical structure of Thymidine 5'-monophosphate (dTMP), a deoxyribonucleotide and one of the building blocks of DNA. ### Description of the Structure: **Thymine Base:** - The thymine base is a pyrimidine ring. - It consists of a six-membered ring with nitrogen atoms at positions 1 and 3, carbonyl groups (=O) at positions 2 and 4, and a methyl group (-CH3) at position 5. - The numbering of the thymine ring is as follows: - Carbon 1 (N) - Carbon 2 (=O) - Carbon 3 - Carbon 4 (=O) - Carbon 5 (CH3) - Carbon 6 (NH) **Deoxyribose Sugar:** - The deoxyribose sugar is a five-membered ring composed of carbon and oxygen. - The carbon atoms in the deoxyribose are numbered as follows: - Carbon 1' (connected to the thymine base) - Carbon 2' (attached to -H instead of -OH making it "deoxy") - Carbon 3' (attached to -OH) - Carbon 4' - Carbon 5' (connected to the phosphate group) **Phosphate Group:** - The phosphate group is attached to the 5' carbon of the deoxyribose sugar. - It consists of one phosphorus atom bonded to four oxygen atoms, with one of the bonds being a double bond. **Important Notations:** - The numbers in red (1, 2, 3, 4, 5, 6) indicate the positions of the atoms in the thymine base. - The numbers in blue (1', 2', 3', 4', 5') indicate the positions of the atoms in the deoxyribose sugar. **Diagram Explanation:** The diagram highlights each component and its connectivity: 1. Thymine is connected to the deoxyribose sugar at the 1' position (N1 of thymine to C1' of deoxyribose). 2. The deoxyribose sugar is linked to the phosphate group at the 5' position (C5' of deoxyribose to the phosphate group). This structural representation
Transcribed Image Text:The image shows the chemical structure of Thymidine 5'-monophosphate (dTMP), a deoxyribonucleotide and one of the building blocks of DNA. ### Description of the Structure: **Thymine Base:** - The thymine base is a pyrimidine ring. - It consists of a six-membered ring with nitrogen atoms at positions 1 and 3, carbonyl groups (=O) at positions 2 and 4, and a methyl group (-CH3) at position 5. - The numbering of the thymine ring is as follows: - Carbon 1 (N) - Carbon 2 (=O) - Carbon 3 - Carbon 4 (=O) - Carbon 5 (CH3) - Carbon 6 (NH) **Deoxyribose Sugar:** - The deoxyribose sugar is a five-membered ring composed of carbon and oxygen. - The carbon atoms in the deoxyribose are numbered as follows: - Carbon 1' (connected to the thymine base) - Carbon 2' (attached to -H instead of -OH making it "deoxy") - Carbon 3' (attached to -OH) - Carbon 4' - Carbon 5' (connected to the phosphate group) **Phosphate Group:** - The phosphate group is attached to the 5' carbon of the deoxyribose sugar. - It consists of one phosphorus atom bonded to four oxygen atoms, with one of the bonds being a double bond. **Important Notations:** - The numbers in red (1, 2, 3, 4, 5, 6) indicate the positions of the atoms in the thymine base. - The numbers in blue (1', 2', 3', 4', 5') indicate the positions of the atoms in the deoxyribose sugar. **Diagram Explanation:** The diagram highlights each component and its connectivity: 1. Thymine is connected to the deoxyribose sugar at the 1' position (N1 of thymine to C1' of deoxyribose). 2. The deoxyribose sugar is linked to the phosphate group at the 5' position (C5' of deoxyribose to the phosphate group). This structural representation
--- ### Multiple Choice Quiz: Identifying Nucleotide Structures Choose the statements that apply to the following figure. **(Choose all correct answers)** - [ ] this structure is a deoxy-ribonucleotide - [ ] contains a pyrimidine base - [ ] contains a purine base - [ ] this structure is a ribonucleotide - [ ] structure is a nucleoside Each option should be carefully evaluated based on the provided figure to determine the correct characteristics of the depicted structure. Understanding these basic concepts is crucial to grasp more complex aspects of nucleotide chemistry and molecular biology. --- (Note: As there is no figure provided in the image, please insert the appropriate figure in the space referenced above to ensure the completeness and accuracy of the educational content.)
Transcribed Image Text:--- ### Multiple Choice Quiz: Identifying Nucleotide Structures Choose the statements that apply to the following figure. **(Choose all correct answers)** - [ ] this structure is a deoxy-ribonucleotide - [ ] contains a pyrimidine base - [ ] contains a purine base - [ ] this structure is a ribonucleotide - [ ] structure is a nucleoside Each option should be carefully evaluated based on the provided figure to determine the correct characteristics of the depicted structure. Understanding these basic concepts is crucial to grasp more complex aspects of nucleotide chemistry and molecular biology. --- (Note: As there is no figure provided in the image, please insert the appropriate figure in the space referenced above to ensure the completeness and accuracy of the educational content.)
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