0.7 Male Total population Female 0.6 0.5Lu 20 70 30 40 50 60 20 30 40 50 60 70 Age (yrs) Age (yrs) Fig 1. The probability of severe asthma as a function of age and stratified by gender. [A] The association between age and the probability of severe asthma by applying a LOWESS (Locally Weighted Scatterplot Smoother) smoother in the overall population. The relationship between age and probability of severe asthma resembles a spline with an inflection point at the age of 45 years. [B] The stratification by gender shows the probability of asthma severity is higher in men than women after age 45.

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Please explain both figures separately please do so!!!!

Male
Total population
Female
0.5
20
30
40
50
60
70
20
30
70
40
50
Age (yrs)
60
Age (yrs)
Fig 1. The probability of severe asthma as a function of age and stratified by gender. [A] The association between age and the probability of severe
asthma by applying a LOWESS (Locally Weighted Scatterplot Smoother) smoother in the overall population. The relationship between age and probability of
severe asthma resembles a spline with an inflection point at the age of 45 years. [B] The stratification by gender shows the probability of asthma severity is
higher in men than women after age 45.
Transcribed Image Text:Male Total population Female 0.5 20 30 40 50 60 70 20 30 70 40 50 Age (yrs) 60 Age (yrs) Fig 1. The probability of severe asthma as a function of age and stratified by gender. [A] The association between age and the probability of severe asthma by applying a LOWESS (Locally Weighted Scatterplot Smoother) smoother in the overall population. The relationship between age and probability of severe asthma resembles a spline with an inflection point at the age of 45 years. [B] The stratification by gender shows the probability of asthma severity is higher in men than women after age 45.
0.8
A
B
Men
Women
0.6
Age: >45 yrs
0.4-
Age: >45 yrs
0.2-
Age: between 18-45 yrs
Age: between 18-45 yrs
0 10
20 30
40
50 60 0
10 20
30
40
50 60
Asthma Duration (yrs)
Asthma Duration (yrs)
Fig 4. Probability of severe asthma as a function of asthma duration, stratified by gender. The
probability of severe asthma in men [A] and in women [B] as a function of asthma duration stratified by age
group comparing older asthma to young adult asthma. The fitted final logistic regression model, which
included variables associated with severe asthma and adjusted for asthma duration, a history of Gastro-
esophageal Reflux Disease (GERD) and a history of nasal corticosteroids, was used to calculate the
probability of severe asthma. Young men and women have a 2% and 4%, increased risk of severe asthma
per year of asthma duration, respectively. After age 45, the risk of severe asthma in women is not impacted
by asthma duration, whereas risk of severe asthma in men continues to increase with increasing asthma
duration.
Probability of Severe Asthma
Transcribed Image Text:0.8 A B Men Women 0.6 Age: >45 yrs 0.4- Age: >45 yrs 0.2- Age: between 18-45 yrs Age: between 18-45 yrs 0 10 20 30 40 50 60 0 10 20 30 40 50 60 Asthma Duration (yrs) Asthma Duration (yrs) Fig 4. Probability of severe asthma as a function of asthma duration, stratified by gender. The probability of severe asthma in men [A] and in women [B] as a function of asthma duration stratified by age group comparing older asthma to young adult asthma. The fitted final logistic regression model, which included variables associated with severe asthma and adjusted for asthma duration, a history of Gastro- esophageal Reflux Disease (GERD) and a history of nasal corticosteroids, was used to calculate the probability of severe asthma. Young men and women have a 2% and 4%, increased risk of severe asthma per year of asthma duration, respectively. After age 45, the risk of severe asthma in women is not impacted by asthma duration, whereas risk of severe asthma in men continues to increase with increasing asthma duration. Probability of Severe Asthma
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