. Patch clamp recording of a single ion channel yields the following results:         Holding Potential (mV) Measured Current (pA) -100 -1.0 -50 0.0 0 +1.0 +50 +2.0 +100 +3.0 What is the electrical resistance (in ohms) of this channel? (keep in mind mV = 10-3  volts, pA = 10-12 amperes, and an ohm is a derived unit that is equivalent to a volt/ampere, i.e. a V/A). a.) 1 x 1010 ohms b.) 2 x 1011 ohms c.) 5 x 1010 ohms d.) 2 x 10-11 ohms e.) 5 x 10-10 ohms   b. What is the conductance of this channel in siemens (S)? (keep in mind 1 S = 1/ohm) a.) 2 x 1011 S b.) 5 x 1010 S c.) 1 x 10-11 S d.) 2 x 10-11 S e.) 5 x 10-10 S

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a. Patch clamp recording of a single ion channel yields the following results:

       

Holding Potential (mV)

Measured Current (pA)

-100

-1.0

-50

0.0

0

+1.0

+50

+2.0

+100

+3.0

What is the electrical resistance (in ohms) of this channel? (keep in mind mV = 10-3  volts, pA = 10-12 amperes, and an ohm is a derived unit that is equivalent to a volt/ampere, i.e. a V/A).
a.) 1 x 1010 ohms
b.) 2 x 1011 ohms
c.) 5 x 1010 ohms
d.) 2 x 10-11 ohms
e.) 5 x 10-10 ohms
 
b. What is the conductance of this channel in siemens (S)? (keep in mind 1 S = 1/ohm)
a.) 2 x 1011 S
b.) 5 x 1010 S
c.) 1 x 10-11 S
d.) 2 x 10-11 S
e.) 5 x 10-10 S
 
c. What would be the equivalent conductance of 1,000 of these channels opened at the same time?
a.) 1000 x conductance of 1 channel
b.) 5 x 10-8 S
c.) 2 x 10-14 S
d.) 1/1000 the conductance of 1 channel
e.) 2 x 108 S
 
 
 
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