Veronica_Perez_Act_III_The_Cure_Workbook

Presence or Absence of END Mean Relative Activity (% of observed max) of GPR Dummy code Absence 6.6 0 Absence 7.4 0 Absence 8.6 0 Absence 6.3 0 Absence 8.9 0 Absence 9.4 0 Absence 9 0 Absence 6.7 0 Absence 4.5 0 Absence 5.6 0 Presence 98.9 1 Presence 99.8 1 Presence 99.5 1 Presence 99.3 1 Presence 98 1 Presence 97.5 1 Presence 98.2 1 Presence 98.1 1 Presence 97.8 1 Presence 99.5 1

Absent Present 0 10 "Absence or Presence of END01" "Mean rea

Presence or Absence of END Mean Relative Activity (% of observed max) of GPR Dummy codes Absence 6.6 0 Absence 7.4 0 Absence 8.6 0 Absence 6.3 0 Absence 8.9 0 Absence 9.4 0 Absence 9 0 Absence 6.7 0 Absence 4.5 0 Absence 5.6 0 Presence 98.9 1 Presence 99.8 1 Presence 99.5 1 Presence 99.3 1 Presence 98 1 Presence 97.5 1 Presence 98.2 1 Presence 98.1 1 Presence 97.8 1 Presence 99.5 1

Absent Present 0 10 20 30 "Absence or Presence of END01" "Mean realtive

Presence or Absence of ENDO1 Mean Relative Activity (% of observed max) of TRPV Absence 1.6 Absence 1.3 Absence 1.1 Absence 1.7 Absence 1.5 Absence 1.6 Absence 1.4 Absence 2 Absence 1.3 Absence 1 Presence 1.9 Presence 0.6 Presence 1.8 Presence 0.9 Presence 1.4 Presence 1.7 Presence 1.5 Presence 1.3 Presence 1.4 Presence 1.3 This sheet contains the or presence of endocan activities per category, a These data will be used Use the Excel sheets (ta 10 Effect of ENDO1 on T modeling, and graphing

Mean r

Presence or Absence of ENDO1 Mean Relative Activity (% of observed max) of TRPV Dummy codes Absence 1.6 0 Absence 1.3 0 Absence 1.1 0 Absence 1.7 0 SD Absence 1.5 0 Absent 1.45 Absence 1.6 0 Present 1.4 Absence 1.4 0 Absence 2 0 Absence 1.3 0 Absence 1 0 Presence 1.9 1 Presence 0.6 1 Presence 1.8 1 Presence 0.9 1 Presence 1.4 1 Presence 1.7 1 Presence 1.5 1 Presence 1.3 1 Presence 1.4 1 Presence 1.3 1

Use the raw data in this tab to estimate the standard deviation of the linear relationship between the categorical independent variable (absence or presence of ENDO1) and the activity of TRPV. Additionally, use these data to estimate the mean activity of TRPV in both the absence and presence of ENDO1. These are for questions 7-10. Use this Excel sheet for calculations. Round all calculated values to the nearest tenth of a decimal place. For example, if you calculate the value as 5.252%, round to 5.3%.

This sheet contains Figure shows two signaling pathw The left box shows a comp of the signaling pathway in (healthy signaling pathway The right box shows an inc diagram of the signaling p tumor cells (cancerous sig pathway).

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***TA im having trouble moving my inhibition line to the "TRPV BLUE" area This sheet (tab) includes an incomplete diagram cancerous signaling pathway in breast tissue. Fo five steps below to complete the pathway whe is present. To add a symbol to the incomplete "Cancerous Signaling Pathway" diagram, right-click on eac in the "Icons for Completing the Cancerous Pa key and select "copy." Then, paste this icon an to the desired position in the incomplete diag Keep in mind the following assumptions as you your diagram: 1) the proteins/processes in the signaling pathw presented in the sequence in which they intera (2) any receptor (GPR or TRPV) activated in the of ENDO1 can directly activate (or inhibit) only of protein or process in the cytoplasm.

m of the Follow the en ENDO1 s ch symbol athway" nd drag it gram. u complete way are act, and e presence one type