PhysioEx Exercise 2 Activity 6

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Sierra College *

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006

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Mechanical Engineering

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Dec 6, 2023

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10

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3/8/2021 PhysioEx Exercise 2 Activity 6 https://media.pearsoncmg.com/bc/bc_0media_ap/physioex/10/ex2/act6/ 1/10 PhysioEx Lab Report Exercise 2: Skeletal Muscle Physiology Activity 6: The Skeletal Muscle Length-Tension Relationship Name: Angelica Date: 8 March 2021 Session ID: session-0e9e886f-7131-6307-2ec1-f2fa73f6bcc0 Pre-lab Quiz Results You scored 100% by answering 5 out of 5 questions correctly. Experiment Results Predict Question Stop & Think Question During an isometric contraction You correctly answered: the skeletal muscle is generating force, but it remains at a fixed length. 1 The force that results from muscles being stretched is You correctly answered: passive force. 2 Active force You correctly answered: is determined by the amount of myosin bound to actin. 3 When you generate the isometric length-tension curve, which of the following forces will not be indicated on your screen? You correctly answered: tetanic force. 4 Passive force in skeletal muscle is largely caused by You correctly answered: the protein titin. 5 Predict Question: As the resting length of the muscle is changed, what will happen to the amount of total force the muscle generates during the stimulated twitch? Your answer: An increase in muscle length will increase total force. 1 Note the dip in total force at a muscle length of 90 mm as compared to the total force at a muscle length of 80 and 100 mm. Why does this occur? 1
3/8/2021 PhysioEx Exercise 2 Activity 6 https://media.pearsoncmg.com/bc/bc_0media_ap/physioex/10/ex2/act6/ 2/10 Experiment Data Voltage (v) Length (mm) Active Force Passive Force Total Force 8.5 75 1.82 0 1.82 8.5 70 1.75 0 1.75 8.5 65 1.55 0 1.55 8.5 60 1.21 0 1.21 8.5 55 0.73 0 0.73 8.5 50 0.11 0 0.11 8.5 80 1.75 0.02 1.77 8.5 90 1.21 0.25 1.46 8.5 100 0.11 1.75 1.86 Muscle Length = 75 mm Active Force = 1.82 Passive Force = 0 Total Force = 1.82 Muscle Length = 75 mm Active Force = 1.82 Passive Force = 0 Total Force = 1.82 Muscle Length = 70 mm You correctly answered: At this muscle length, active force has decreased in value and passive force has not yet increased to a significant value. Active Force Active Force Passive Force Passive Force Total Force Total Force
3/8/2021 PhysioEx Exercise 2 Activity 6 https://media.pearsoncmg.com/bc/bc_0media_ap/physioex/10/ex2/act6/ 3/10 Active Force = 1.75 Passive Force = 0 Total Force = 1.75 Muscle Length = 70 mm Active Force = 1.75 Passive Force = 0 Total Force = 1.75 Muscle Length = 65 mm Active Force = 1.55 Passive Force = 0 Total Force = 1.55 Muscle Length = 65 mm Active Force = 1.55 Passive Force = 0 Active Force Active Force Passive Force Passive Force Total Force Total Force Active Force Active Force Passive Force Passive Force Total Force Total Force
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3/8/2021 PhysioEx Exercise 2 Activity 6 https://media.pearsoncmg.com/bc/bc_0media_ap/physioex/10/ex2/act6/ 4/10 Total Force = 1.55 Muscle Length = 60 mm Active Force = 1.21 Passive Force = 0 Total Force = 1.21 Muscle Length = 60 mm Active Force = 1.21 Passive Force = 0 Total Force = 1.21 Muscle Length = 55 mm Active Force = 0.73 Passive Force = 0 Active Force Active Force Passive Force Passive Force Total Force Total Force
3/8/2021 PhysioEx Exercise 2 Activity 6 https://media.pearsoncmg.com/bc/bc_0media_ap/physioex/10/ex2/act6/ 5/10 Total Force = 0.73 Muscle Length = 55 mm Active Force = 0.73 Passive Force = 0 Total Force = 0.73 Muscle Length = 50 mm Active Force = 0.11 Passive Force = 0 Total Force = 0.11 Muscle Length = 50 mm Active Force = 0.11 Passive Force = 0 Active Force Active Force Passive Force Passive Force Total Force Total Force Active Force Active Force Passive Force Passive Force Total Force Total Force
3/8/2021 PhysioEx Exercise 2 Activity 6 https://media.pearsoncmg.com/bc/bc_0media_ap/physioex/10/ex2/act6/ 6/10 Total Force = 0.11 Muscle Length = 80 mm Active Force = 1.75 Passive Force = 0.02 Total Force = 1.77 Muscle Length = 80 mm Active Force = 1.75 Passive Force = 0.02 Total Force = 1.77 Muscle Length = 90 mm Active Force = 1.21 Passive Force = 0.25 Active Force Active Force Passive Force Passive Force Total Force Total Force
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3/8/2021 PhysioEx Exercise 2 Activity 6 https://media.pearsoncmg.com/bc/bc_0media_ap/physioex/10/ex2/act6/ 7/10 Total Force = 1.46 Muscle Length = 90 mm Active Force = 1.21 Passive Force = 0.25 Total Force = 1.46 Muscle Length = 100 mm Active Force = 0.11 Passive Force = 1.75 Total Force = 1.86 Muscle Length = 100 mm Active Force = 0.11 Passive Force = 1.75 Active Force Active Force Passive Force Passive Force Total Force Total Force Active Force Active Force Passive Force Passive Force Total Force Total Force
3/8/2021 PhysioEx Exercise 2 Activity 6 https://media.pearsoncmg.com/bc/bc_0media_ap/physioex/10/ex2/act6/ 8/10 Total Force = 1.86
3/8/2021 PhysioEx Exercise 2 Activity 6 https://media.pearsoncmg.com/bc/bc_0media_ap/physioex/10/ex2/act6/ 9/10 Post-lab Quiz Results You scored 100% by answering 5 out of 5 questions correctly. Review Sheet Results When a skeletal muscle is stimulated and generates force but remains at a fixed length You correctly answered: the muscle is contracting isometrically. 1 Which protein is mostly responsible for the development of passive force in a muscle? You correctly answered: titin. 2 In skeletal muscle, active force stimulated through a range of muscle lengths You correctly answered: will utilize ATP hydrolysis to drive the cross bridge cycle. 3 Which of the following is not depicted in a typical skeletal muscle isometric length-tension curve? You correctly answered: time. 4 Maximal active tension will be produced in a skeletal muscle fiber when You correctly answered: the fiber is at its resting length. 5 What happens to the amount of total force the muscle generates during the stimulated twitch? How well did the results compare with your prediction? Your answer: My prediction was correct, when there is an increase in muscle length, the total force also increases. When there is a decrease in muscle length, there is a decrease in total force. 1 What is the key variable in an isometric contraction of a skeletal muscle? Your answer: The length-tension relationship. 2 Based on the unique arrangement of myosin and actin in skeletal muscle sarcomeres, explain why active force varies with changes in the muscle's resting length. Your answer: When the skeletal muscle's resting length increases, there is more time for myosin bridges to return to their starting positions. 3
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3/8/2021 PhysioEx Exercise 2 Activity 6 https://media.pearsoncmg.com/bc/bc_0media_ap/physioex/10/ex2/act6/ 10/10 What skeletal muscle lengths generated passive force? (Provide a range.) Your answer: 80mm to 100mm range. 4 If you were curling a 7-kg dumbbell, when would your bicep muscles be contracting isometrically? Your answer: As you lift/curl the 7-kg dumbbell up, your bicep muscles will contract isometrically. 5