A&P2+LABREPORT

Chemistry You are the only doctor in a clinic that is cut off from the outside world by violent storms and landslides. A 30-year-old woman suffering from tachycardia is brought in. You can see she is likely to die without treatment, and although you have very few drugs, you have propranolol, a beta blocker, in injectable vials. You decide to give the woman intravenous propranolol. The pharmacokinetics of propranolol include a clearance of 50L/hour and a half-life of 3 hours. If an intravenous infusion of propranolol is started at a rate of 0.5mg/minute, approximately how long would it take to reach 93.75% of the final steady-state concentration? 3 hours 50 minutes It would depend on the dosage 12 hours

Case Studies An 18-year-old male high school student who had a 4-year history of diabetes mellitus was brought to the emergency department because of excessive drowsiness, vomiting. and diarrhea. His diabetes had been well controlled with 40 units of NPH insulin daily until several days ago when he developed excessive thirst and polyuria. For the past 3 days, he has also had headaches, myalgia, and a low-grade fever. Diarrhea and vomiting began 1 day ago Chemistry Test Results Sodium 126 mmol/L Urinalysis Results Specific 1.012 gravity pH 5.0 Glucose 4+ Ketone Large Potassium Chloride Bicarbonate Plasma glucose 6.1 mmol/L 87 mmol/L 6 mmol/L 600 mg/dL BUN Creatinine Serum ketones 48 mg/dL. 2.0 mg/dL 4+ 1. What is the probable diagnosis of this patient 2. What laboratory test(s) should be performed to follow this patient and aid in adjusting insulin levels? 3. Why are the urine ketones positive? 4. What methods are used to quantitate urine ketones? Which ketone(s) do they detect?