2021-Final
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Queens University *
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310
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Chemistry
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Feb 20, 2024
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STUDENT NUMBER: ___________________________ page 1 of 18 COURSE NUMBER (310 or 316): _____________________________ QUEEN'S UNIVERSITY FINAL EXAMINATION – APRIL 20 2021 BCHM 310/316* FACULTY OF ARTS AND SCIENCE DEPARTMENT OF BIOMEDICAL & MOLECULAR SCIENCES Course Coordinator: Dr. G. Jones DEPARTMENT USE ONLY 1 2 3 4 5 6 7 8 SAQ MCQ Total TIME ALLOWED
: 3 HOURS SECTIONS A & B
CONSIST OF 48 MULTIPLE-CHOICE ANSWER QUESTIONS worth 1.25 marks each. Make sure to put your STUDENT IDENTIFICATION NUMBER
on the multiple choice answer sheet. ANSWER ALL OF THE QUESTIONS
. There is no penalty for an incorrect answer. For each multiple-
choice question indicate the BEST
or most appropriate answer by blackening, in pencil,
the appropriate vertically-dotted area on the ANSWER SHEET
. Incorrect answers may be erased. SECTION C
CONSISTS OF 8 Essay ANSWER QUESTIONS
worth 5 marks each. ANSWER ALL OF THEM
in the space provided. Write your STUDENT IDENTIFICATION NUMBER
and COURSE NUMBER
(310 or 316) at the top of this page and on the multiple choice answer sheet. Finally, hand in BOTH
the QUESTION SHEET and the ANSWER SHEET. Please note: “Proctors are unable to respond to queries about the interpretation of exam questions. Do your best to answer the exam questions as written.” "This material is copyrighted and is for the sole use of students registered in BCHM 310/316 and writing this exam. This material shall not be distributed or disseminated. Failure to abide by these conditions is a breach of copyright and may also constitute a breach of academic integrity under the University Senate's Academic Integrity Policy Statement."
SECTION A Page 2 of 18 For each question in this section blacken the area which corresponds to the BEST answer. A single answer is required for each question. 1.
Which of the following
enzymes/pathways is INCORRECTLY listed with
its subcellular
location
:
a. glucose-6-phosphatase- lumen of endoplasmic reticulum
b. pyruvate dehydrogenase
- cytoplasm c. malate dehydrogenase- mitochondrion d. inactive hexokinase IV (glucokinase)- nucleus e. phospholipid biosynthesis- endoplasmic reticulum 2.
Identify the following steroidal molecule:
a. testosterone b. estradiol c. 25-hydroxyvitamin D
3
d. cortisol e. progesterone 3. The CORRECT
sequence of intermediates (not all shown in each answer) in the Urea Cycle
is: a. citrulline, ornithine, aspartate, arginine b. argininosuccinate, aspartate, fumarate, urea c. ornithine, aspartate, citrullyl-AMP, arginine, urea d. citrulline, argininosuccinate, urea, arginine e. carbamoyl phosphate, argininosuccinate, arginine, ornithine 4. Which of the following amino acids is BOTH glucogenic and
ketogenic
? a. alanine b. aspartate c. glutamate d. tryptophan e. serine
SECTION A Page 3 of 18
For each question in this section blacken the area which corresponds to the BEST answer. A single answer is required for each question. 5. Which of the following statements about ω-oxidation of fatty acids is
CORRECT: a. it involves sequentially acid, aldehyde and alcohol intermediates b. it involves a cytochrome P450, molecular oxygen & NADPH to oxidize the ω-carbon c. it uses catalase to regenerate FAD d. it shortens the fatty acid by cleaving off a C-2 unit e. it prepares the very long-chain chain fatty acid for mitochondrial β-oxidation 6. The following coenzyme is involved in: a. methylation b. single carbon transfer c. carboxylation d. hydroxylation e. transamination 7. The lipid structure below is best classified as: a. 1-steroyl, 2-linolenoyl phosphatidyl ethanolamine b. 1-oleoyl, 2-linoleoyl phosphatidyl inositol c. 1-palmitoyl, 2-linolenoyl phosphatidyl glycerol d. 1-palmitoyl, 2-linolenoyl phosphatidyl serine e. 1-steroyl, 2-linoleoyl phosphatidyl choline
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SECTION A Page 4 of 18 For each question in this section blacken the area which corresponds to the BEST answer. A single answer is required for each question. 8. Which of the following statements about isoprenoid biosynthesis is
INCORRECT: a. isoprene units are branched 5-carbon modules made by decarboxylation of mevalonate b. isoprenoid synthesis involves the mitochondrial enzyme HMG-CoA synthase c. the rate limiting step of isoprenoid biosynthesis is HMG-CoA reductase d. intermediates in the pathway such as C
5
, C
10
& C
15
are made as pyrophosphate derivatives e. squalene, a C
30
linear isoprenoid, is cyclized into a C30 steroidal structure, lanosterol 9. Which of the following statements about the regulation of Acetyl CoA carboxylase is CORRECT
: a. It is inactivated by insulin b. it is dephosphorylated by leptin and adiponectin c. it is phosphorylated by a kinase stimulated by glucagon d. it is partially activated by citrate e. it is allosterically inhibited by malonyl CoA 10. Which of the following is NOT
a component part of a ganglioside
: a. N-acetylgalactosamine b. arachidonate c. N-acetylneuraminic acid d. palmitate e. sphingosine 11. Identify the following isoprenoid: Is it: a. mevalonate b. dihydrofolate c. ubiquinone d. dihydrobiopterin e. squalene
SECTION A Page 5 of 18 For each question in this section blacken the area which corresponds to the BEST answer. A single answer is required for each question. 12. Which enzyme is the main determinant of the rate of the glyoxylate cycle
: a. citrate synthase b. aconitase c. isocitrate lyase d. isocitrate dehydrogenase e. malate synthase 13. Which is the principal
anapleurotic pathway
to maintain the citric acid cycle in heart muscle
: a. pyruvate carboxylase b. malic enzyme c. PEP carboxykinase d. PEP carboxylase e. pyruvate dehydrogenase 14. Useable water production from complete b
-oxidation of palmitate from a tri-palmitoyl glyceride molecule metabolized to CO
2
and ATP arises from: a. hydrolysis of the triglyceride b. 4 steps of b
-oxidation of the palmitate residues c. the steps of the citric acid cycle d. oxidative phosphorylation of NADH and FADH
2 e. electron transport chain processing of NADH and FADH
2 15.
Which of the following statements regarding important metabolic pathways is INCORRECT:
a. pyruvate kinase is inactive in the fasting liver b. pyruvate carboxylase and PEP carboxykinase are absent from adipocytes c. glucose-6-phosphatase is absent from muscle d. glycerol kinase is absent from adipocytes e. 3
b
-ketoacyl-CoA-transferase is absent from the liver
SECTION A Page 6 of 18 For each question in this section blacken the area which corresponds to the BEST answer. A single answer is required for each question. 16. When ATP, ADP & Pi concentrations are at normal cellular concentrations, the pH is 7.0, the temperature is 25°C and the pressure is 101.3 kPa, the actual free energy of hydrolysis of ATP, ΔGp, in erythrocytes is: a. -30.5 kJ/mol b. -43 kJ/mol c. -52 kJ/mol d. -63 kJ/mol e. -75 kJ/mol 17. Which of the following statements about the citric acid cycle
is INCORRECT
: a. it involves succinyl CoA synthetase which can use GDP or ADP b. it directly generates the reducing equivalents 3 NADH and 1 FADH
2
per cycle c. it generates succinyl CoA which can be syphoned off to make heme d. it involves the generation of two molecules of H
2
O per cycle e. it involves oxidative decarboxylation steps using thiamine pyrophosphate as a coenzyme 18. Which of the following would be INCORRECT
for the composition of VLDL
a. apolipoprotein CII b. 50% triglycerides c. 7% cholesterol d. 18% phospholipids e. 25% cholesteryl esters 19. Liver
contains which of the following combinations of transporters, enzymes and receptors: a. GLUT2, hexokinase I and ONLY glucagon receptor b. GLUT4, hexokinase IV and BOTH glucagon and epinephrine receptors c. GLUT2, hexokinase IV and ONLY glucagon receptor d. GLUT4, hexokinase I and ONLY epinephrine receptor e. GLUT2, hexokinase IV, and BOTH glucagon and epinephrine receptors
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SECTION A Page 7 of 18 For each question in this section blacken the area which corresponds to the BEST answer. A single answer is required for each question. 20. Which of the following statements regarding bioenergetics & the electron transport chain is CORRECT:
a. the standard reduction potential, E°
¢
of any half-reaction with 1M oxidised and reduced species in the test cell at pH 7.0, measured using a hydrogen electrode in which H
2
gas at 101.3 kPa is in contact with 1 M H
+
, also at pH = 7.0, and arbitrarily assigned an emf value of 0.00 volts b. by convention, the standard reduction potential, E°
¢
of any half reaction is depicted with the oxidised species on the left and the reduced species on the right c. E°
¢
for half reaction involving O
2
+ 2H
+
+ 2 electrons à
H
2
O has a strongly positive value. d. for the electron transport chain to work properly electron donors must pass on electrons to acceptors with half reactions with a more negative E°
¢
e. when two half reactions are combined, then by convention: ΔE°
¢
= E°
¢
of the electron donor minus E°
¢
of the electron acceptor 21. When acting upon PIP
2
(Phosphatidyl 4,5-bisphosphate) phospholipase C
cleaves: a. the C-O bond between the glycerol and the 1-phosphate b. the O-P bond between the glycerol and the 1-phosphate c. the P-O bond between the 1-phosphate and the inositol ring d. the O-C bond between the 1-phosphate and the inositol ring e. the C-O bond between the inositol ring and the 4-phosphate 22. Which of the following statements about carbohydrate biochemistry is INCORRECT
: a. mannose is an epimer of glucose differing in stereochemistry ONLY at C-4 b. in determination of D- & L-configuration, the reference carbon for glucose is C-5 c. the anomeric carbon of glucose is C-1 d. fructose is a 6-carbon ketose e. glucose exists in solution as two 6-membered ring structures a
- and b
-glucopyranose 23. Pyridoxal phosphate is a coenzyme for which of the following reactions:
a. transamination b. dehydrogenation c. carboxylation d. decarboxylation e. hydroxylation
SECTION A Page 8 of 18 For each question in this section blacken the area which corresponds to the BEST answer. A single answer is required for each question. 24. Statins block which of the following enzymes: a. 5-lipoxygenase (5-LO) b. phospholipase A2 c. cyclo-oxygenase-2 (COX-2) d. HMG-CoA reductase e. cyclic nucleotide phosphodiesterase -END OF SECTION A-
SECTION B Page 9 of 18 For the following questions, ONE or MORE of the statements (a-d) are correct. Indicate on your answer sheet which letter A through E is the correct answer (A) if only a, b and c are correct (B) if only a and c are correct (C) if only b and d are correct (D) if only d is correct (E) if ALL are correct 25. Glycolysis: a. forms NADH during anaerobic periods which can be recycled to NAD via lactate dehydrogenase b. consumes 2 ATPs during the initial preparatory phase c. operates in cancer cells under anaerobic conditions & at 10x the rate of normal tissues d. involves a NET
production of 5-7 ATPs/glucose molecule en route to pyruvate (A) O
if only a, b and c are correct (B) O
if only a and c are correct (C) O
if only b and d are correct (D) O
if only d is correct (E) O
if ALL are correct 26. Thiamine pyrophosphate is a coenzyme for one or more steps within which of the following pathways: a. pentose phosphate pathway b. ketogenesis c. citric acid cycle d. glycolysis (A) O
if only a, b and c are correct (B) O
if only a and c are correct (C) O
if only b and d are correct (D) O
if only d is correct (E) O
if ALL are correct 27. Pancreatic Lipase action involves: a. partial lipolysis of the triglyceride core to 2-monoglyceride and two “free” fatty acids b. the assistance of a bile acid such as taurocholic acid to emulsify the dietary fat c. a co-lipase for the enzyme to gain access to the interior of the lipid vesicle d. the acid pH environment of the intestine to provide optimal rates of catalysis
(A) O
if only a, b and c are correct (B) O
if only a and c are correct (C) O
if only b and d are correct (D) O
if only d is correct (E) O
if ALL are correct
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SECTION B Page 10 of 18 For the following questions, ONE or MORE of the statements (a-d) are correct. Indicate on your answer sheet which letter A through E is the correct answer (A) if only a, b and c are correct (B) if only a and c are correct (C) if only b and d are correct (D) if only d is correct (E) if ALL are correct 28. NADPH is generated by which of the following enzymes
: metabolic steps
: a. glucose-6-phosphate dehydrogenase
: glucose 6-phosphate -> 6-phosphoglucono-lactone b. malic enzyme
: malate -> oxaloacetate c. 6-phosphogluconate dehydrogenase
: 6-phosphogluconate -> ribulose 5-phosphate d. α-ketoglutarate dehydrogenase:
α-ketoglutarate -> succinyl CoA
(A) O
if only a, b and c are correct (B) O
if only a and c are correct (C) O
if only b and d are correct (D) O
if only d is correct (E) O
if ALL are correct 29. Fatty acid movement and metabolism inside the cell involves: a. lipoprotein lipase to free the fatty acid from triglyceride inside the cell b. non-covalent binding of the free fatty acid to cellular fatty acid binding protein c. thiolase to complex the fatty acyl group to CoA d. transport of the fatty acyl group bound to carnitine across the inner mitochondrial membrane (A) O
if only a, b and c are correct (B) O
if only a and c are correct (C) O
if only b and d are correct (D) O
if only d is correct (E) O
if ALL are correct 30. Which of the following molecules is paired CORRECTLY with its direct precursor
from the citric acid cycle or glycolysis: a. glutamate
; ∝
-ketoglutarate b.
heme;
succinyl CoA c. aspartate
; oxaloacetate d
. serine
; 3-phosphoglycerate
(A) O
if only a, b and c are correct (B) O
if only a and c are correct (C) O
if only b and d are correct (D) O
if only d is correct (E) O
if ALL are correct
SECTION B Page 11 of 18 For the following questions, ONE or MORE of the statements (a-d) are correct. Indicate on your answer sheet which letter A through E is the correct answer (A) if only a, b and c are correct (B) if only a and c are correct (C) if only b and d are correct (D) if only d is correct (E) if ALL are correct 31. Which of the following enzymes
couples with
inorganic pyrophosphatase
to provide the energy released from iPP to drive its/their respective reactions: a. UDP-glucose pyrophosphorylase b. fatty acyl CoA synthetase c. methionine adenosyl transferase d. glycogen phosphorylase (A) O
if only a, b and c are correct (B) O
if only a and c are correct (C) O
if only b and d are correct (D) O
if only d is correct (E) O
if ALL are correct 32. Which of the following statements about the biosynthesis of docosahexaenoic acid (DHA) from an essential fatty acid
in mammals is (are)
CORRECT: a. the initial steps alternate between firstly
a) desaturation and then
b) elongation steps b. desaturation steps involve sequentially: Δ
6
-desaturase, Δ
5
-desaturase & Δ
6
-desaturase again c. it starts with linolenate, 18:3Δ
9,12,15 and involves the intermediate 24:6Δ
6,9,12,15,18,
21 d. the final step involves removal of a C-2 unit by β-oxidation in the mitochondrion (A) O
if only a, b and c are correct (B) O
if only a and c are correct (C) O
if only b and d are correct (D) O
if only d is correct (E) O
if ALL are correct 33. Which of the following enzymes is (are) involved in substrate-level phosphorylation
? a. phosphoglycerate kinase b. succinyl-CoA synthetase c. pyruvate kinase d. pyruvate carboxylase (A) O
if only a, b and c are correct (B) O
if only a and c are correct (C) O
if only b and d are correct (D) O
if only d is correct (E) O
if ALL are correct
SECTION B Page 12 of 18 For the following questions, ONE or MORE of the statements (a-d) are correct. Indicate on your answer sheet which letter A through E is the correct answer (A) if only a, b and c are correct (B) if only a and c are correct (C) if only b and d are correct (D) if only d is correct (E) if ALL are correct 34. Peroxisomal b
-oxidation of fatty acids: a. exists to metabolize medium chain fatty acids b. involves regeneration of FAD from FADH
2
without formation of ATP c. utilizes NADH generated to directly drive a peroxisomal electron transport chain for energy d. allows for acetyl CoA generated to leave the organelle & enter mitochondrion (A) O
if only a, b and c are correct (B) O
if only a and c are correct (C) O
if only b and d are correct (D) O
if only d is correct (E) O
if ALL are correct 35. During the later stages of fasting the brain
becomes dependent upon which of the following enzymes to efficiently generate energy: a. thiolase b. PEP carboxykinase c. 3-ketoacyl CoA transferase d. malate dehydrogenase (A) O
if only a, b and c are correct (B) O
if only a and c are correct (C) O
if only b and d are correct (D) O
if only d is correct (E) O
if ALL are correct 36. Lipid rafts are rich in which of the following: a. cholesterol b. cholesterol ester c. sphingomyelin d. prenylated proteins (A) O
if only a, b and c are correct (B) O
if only a and c are correct (C) O
if only b and d are correct (D) O
if only d is correct (E) O
if ALL are correct
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SECTION B Page 13 of 18 For the following questions, ONE or MORE of the statements (a-d) are correct. Indicate on your answer sheet which letter A through E is the correct answer (A) if only a, b and c are correct (B) if only a and c are correct (C) if only b and d are correct (D) if only d is correct (E) if ALL are correct 37. PI-specific Phospholipase C-
b
subtypes
possess which of the following regulatory domains: a. Src homology domain 3 (SH3) b. pleckstrin homology domain (PH) c. Src homology domain 2 (SH2) d. G-protein binding domain (G) (A) O
if only a, b and c are correct (B) O
if only a and c are correct (C) O
if only b and d are correct (D) O
if only d is correct (E) O
if ALL are correct 38. The FoF
1
ATP Synthase has: a. a rotating cylindrical proton channel made up of between 8-15 c-subunits b. a rotating spindle consisting of γ(gamma) and e
(epsilon) subunits c. a static “stanchion” comprising b- and d
- subunits to connect F
1
to membrane d. a static F
1
domain consisting of 3
b
-subunits which have ADP+ Pi, ATP +H
2
O or are empty (A) O
if only a, b and c are correct (B) O
if only a and c are correct (C) O
if only b and d are correct (D) O
if only d is correct (E) O
if ALL are correct 39. Erythrocytes possess which of the following metabolic enzymes: a. isocitrate dehydrogenase
b. glucose-6-phosphate dehydrogenase
c. pyruvate dehydrogenase d. pyruvate kinase (A) O
if only a, b and c are correct (B) O
if only a and c are correct (C) O
if only b and d are correct (D) O
if only d is correct (E) O
if ALL are correct
SECTION B Page 14 of 18 For the following questions, ONE or MORE of the statements (a-d) are correct. Indicate on your answer sheet which letter A through E is the correct answer (A) if only a, b and c are correct (B) if only a and c are correct (C) if only b and d are correct (D) if only d is correct (E) if ALL are correct 40. Tetrahydrobiopterin is a coenzyme involved in following reaction(s): a. phenylanlanine -> tyrosine b. tryptophan -> 5-hydroxy-tryptophan c. tyrosine -> L-Dopa (L-3,4-dhydroxyphenylalanine) d. 25-hydroxyvitamin D
3 -> 24,25-dihydroxyvitamin D
3
(A) O
if only a, b and c are correct (B) O
if only a and c are correct (C) O
if only b and d are correct (D) O
if only d is correct (E) O
if ALL are correct 41. Flippases and floppases: a. create phospholipid asymmetry between the two leaflets of a natural membrane b. both move phospholipids across a plasma membrane from the inner to the outer leaflet c. both contain an ATPase activity d. are transporters which allow phospholipid transport by facilitated diffusion (A) O
if only a, b and c are correct (B) O
if only a and c are correct (C) O
if only b and d are correct (D) O
if only d is correct (E) O
if ALL are correct 42. Which phospho-/sphingo-lipids are found mainly in the outer leaflet
of the plasma membrane
: a. phosphatidyl ethanolamine b. phosphatidyl serine c. phosphatidyl inositol d. phosphatidyl choline (A) O
if only a, b and c are correct (B) O
if only a and c are correct (C) O
if only b and d are correct (D) O
if only d is correct (E) O
if ALL are correct
SECTION B Page 15 of 18 For the following questions, ONE or MORE of the statements (a-d) are correct. Indicate on your answer sheet which letter A through E is the correct answer (A) if only a, b and c are correct (B) if only a and c are correct (C) if only b and d are correct (D) if only d is correct (E) if ALL are correct 43. What is significant about carnitine-mediated entry of fatty acids into hepatocyte mitochondrial matrix? a. it controls the substrate concentration thereby limiting the rate of β-oxidation b. it is specific for fatty acids ranging in length from C
16
to C
22
c. the fatty acid is now committed to β-oxidation and cannot leave without being metabolized d. the resultant acetyl CoA formed can be further broken down to CO
2
by the citric acid cycle (A) O
if only a, b and c are correct (B) O
if only a and c are correct (C) O
if only b and d are correct (D) O
if only d is correct (E) O
if ALL are correct 44. Heme biosynthesis involves: a. δ-levulinate as an initial intermediate b. an amino acid precursor, glycine or glutamate c. assembly of 4 porphyrin rings to form protoporphyrin d. insertion of a metal ion, Fe
3+
by the enzyme ferrochelatase (A) O
if only a, b and c are correct (B) O
if only a and c are correct (C) O
if only b and d are correct (D) O
if only d is correct (E) O
if ALL are correct 45. The glycerol-3-phosphate shuttle or bypass: a. transports FADH
2
instead of NADH across the IMM into the mitochondrial matrix b. uses mitochondrial glycerol-3-phosphate dehydrogenase to feed electrons from FADH
2
to ubiquinone c. it is more energy efficient than the alternative malate-aspartate shuttle d. it is faster and therefore used by insect flight muscle (A) O
if only a, b and c are correct (B) O
if only a and c are correct (C) O
if only b and d are correct (D) O
if only d is correct (E) O
if ALL are correct
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SECTION B Page 16 of 18 For the following questions, ONE or MORE of the statements (a-d) are correct. Indicate on your answer sheet which letter A through E is the correct answer (A) if only a, b and c are correct (B) if only a and c are correct (C) if only b and d are correct (D) if only d is correct (E) if ALL are correct 46. Enzymes involved directly or indirectly
in the utilization of ketone bodies for energy in the heart
are: a. β-ketoacyl CoA transferase b. β-hydroxybutyrate dehydrogenase c. thiolase d. PEP carboxykinase (A) O
if only a, b and c are correct (B) O
if only a and c are correct (C) O
if only b and d are correct (D) O
if only d is correct (E) O
if ALL are correct 47. The following molecule or its derivatives are involved in which of the following reactions: a. transfer of -CH
3
groups b. transfer of -H–C=O groups c. transfer of -CH
2
OH groups d. transfer of -CH
2
C=O groups (A) O
if only a, b and c are correct (B) O
if only a and c are correct (C) O
if only b and d are correct (D) O
if only d is correct (E) O
if ALL are correct
SECTION B Page 17 of 18 For the following questions, ONE or MORE of the statements (a-d) are correct. Indicate on your answer sheet which letter A through E is the correct answer (A) if only a, b and c are correct (B) if only a and c are correct (C) if only b and d are correct (D) if only d is correct (E) if ALL are correct 48. Fatty acid Synthase: a. generates a palmitate molecule in which each C
2
-unit is derived from malonyl CoA b. uses a telescopic pantetheine arm of ACP to reach the malonyl group on the condensing enzyme c. employs the reducing power of NADH in two reduction steps d. transcription is increased by a low-fat diet (A) O
if only a, b and c are correct (B) O
if only a and c are correct (C) O
if only b and d are correct (D) O
if only d is correct (E) O
if ALL are correct -END OF SECTION B-
SECTION C Short Answer Questions Page 18 of 18 49. Briefly
outline the signal transduction steps
& enzymatic events
involved in glucagon’s
action on stored materials
in the muscle. (5 marks) 50. Provide a detailed description of the steps of Mitochondrial Fatty Acid β-Oxidation. Describe briefly in a sentence or two
how it is regulated. (5 marks)
51. Starting with glycerol & free fatty acids, describe the biosynthesis of phosphatidyl inositol in the liver.
(5 marks). 52. Pyruvate dehydrogenase
uses a number of coenzymes. Describe their role in facilitating the overall reaction? (5 marks) 53. Fructose-2,6-bisphosphate
plays a crucial role in regulation of glycolysis and gluconeogenesis. What exactly does it do and how is its concentration regulated? (5 marks) 54. Describe the signal transduction events in the action of i
nsulin
on glucose transporters and glycogen synthase
in the muscle. (5 marks)
55.
Compare and contrast the action of inhibitors versus uncouplers
of electron transport chain & oxidative phosphorylation (5 marks). In your answer give an example of each. 56. How are the potentially toxic -NH2 groups of amino acids
delivered from peripheral tissues to the liver
for excretion through the urea cycle? How does this process differ in the muscle
? (5 marks) .
-END OF EXAM-
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troduction to MasteringChemistry
2 of 15
roduction to Numeric Answers
Part B
When entering large numbers in the answer box, do not use commas. For example, enter 1276400 for the number 1,276,400. Do not enter 1, 276, 400. If you accidentally
enter commas, you will receive feedback as a reminder. Answer the following question by typing the numeric answer into the answer box. What is the sum of 9260 and
3240?
Express your answer numerically to at least three significant figures.
• View Available Hint(s)
Eν ΑΣφ
sum =
Submit
Scientific notation
You may want to enter 367.000 000 in scientific notatinn as 3 67 x 10° There are twn ways to do this
P Pearson
Dormicdonc Contact l.
Copuriaht 0207 0 Doarcen Education Inc Alrightr rorornd Armr
12:58
hp
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- Chapter 8 Homew X
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Statistics- Achieve
Orgo Connect A Orgo - Aleks French Mind Tap 4G
omework Alkyl Halides and Eliminati. G
2 attempts left
券
Check my work
What alkyl halide forms the following alkene as the only product in an elimination reaction?
Click the "draw structure" button to launch the drawing utility.
draw structure
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MacBookAir
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Conte
Meas
Take
G Three
Pears
Maste
G 4.988
Ta X
G Three
G Three
D Spani
->
A dmacc.blackboard.com/webapps/assessment/take/launch.jsp?course_assessment_id%= 402371 1&course_id%3 94346 18&ne
pps
Work for students...
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CHM
* Question Completion Status:
QUESTION 2
Three separate lab groups determined the density of a metal to be 12.5 g/mL, 13.1 g/mL and 14.8 g/mL. Use these values to
calculate the average density among the measurements.
O A. 13.5 g/mL
O B. 30.5 g/mL
ОС. 13.1 g/mL
O D. 10.1 g/mL
QUESTION 3
Three senarate lah grouns determined the density of a metal to be 12.5 g/mL, 13.1 g/mL and 14.8 g/mL. If the accepted de
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F2
© Macmillan Learning
NO₂
Incorrect
#
3
20
F3
: 0:
||
$
4
F4
078⁰
%
5
BeCL
MacBook Air
< 60
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7
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Calculate mass index
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Predict the product of the following reaction.
1. LDA, -78°C
H.
2.
H.
HDJCMD
но
TH.
MacBook Air
DOO
F4
F3
F2
FI
23
%24
3.
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As a material expands its weight per unit of volume (also called density) _______ ?
Group of answer choices
Changes unpredictably
Decreases
Increases
Stays the same
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Dipping into health
When blood pressure is measured over a 24-hour period, this is referred to as ambulatory blood
pressure monitoring, three patterns arise. Here are samples of three different individual.
Let's call them Dick (1), Tom (2) and Harry (3).
1
2
3
Patient's
Paticnt's
BP
BP
Palicet's
Upper
limit
Upper
limit
12
Upper
lim
124
120
Lower
limit
Lower
Lower
limit
Time (houn after wakening)
Time (hours after awakening)
Time (hours after awakenin
SYSTOLIC BP (mm Hg)
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Listed in the Item Bank are key terms and expressions, each of which is associated with one of the columns. Drag and drop each item into
the correct column. Order does not matter.
Terms
Extrinsic properties (also called extensive) are directly related to the amount of material being measured. Intrinsic properties (also called
intensive) are those which are independent of the amount of matter present.
Intensive
:: Melting point :: Density :: Length :: Boiling point
Privacy PHONE 1-877-377-9537| FAX 1-877-816-0808 Blog
hp
:: Mass
:: Volume
7 of 8
Extensive
01:01:37
:: Luster :: Color
:: Temperature
Ne
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See Figure 13-10. Which structure best matches the NMR and IR
shown?
O
A
B
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73Ga ? 73Ge + _____
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Aktiv Chemistry
STARTING AMOUNT
+
CLE
SOD
X
X
Aktiv Chemistry
O8 https://app.101edu.co
MAR
30
o Mail THOMPSON, X
Convert 5.88 x 10-6
ADD FACTOR
10
x( )
5.88
1
10-6
10⁹
m
10-⁹
5.88 x 10-4
5.88 x 10-6
(IC) My.UAFS - Students: X
Question 5 of 58
to nanometers. Use only the metric system.
5.88 x 104
5.88 x 10³
0.0588
nm
Zall
=
m
alt
ANSWER
5.88 x 10-15
5.88 x 10-4
0.01
M Inbox (11) - hthomp0 X
1000
588
0.1
RESET
2
58.8
0.001
106
tv A
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Home - LioNet
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For each problem, you must:
1) Calculate the degree of unsaturation.
-1
2) Assign the principal IR absorption bands above 1500 cm
3) Draw the structure of the compound
4) Label the protons on your structure with letters and assign them to peaks on the NMR spectrum
(see the example below).
4.0
C
2H
3.5
3.0
2.5
D
1H
3.0
This peak
is a magnified
version of
this peak
A
2.8
2.0
1H
B
zum
2.6
B
2H
Each problem contains the formula of the compound, the IR spectrum (with axes in cm³¹ vs. %
transmission), and the ¹H NMR spectrum (with axis in PPM shift). Some NMR spectra show a peak
hovering above the baseline. This is a magnified view of one of the actual peaks, to allow you to see
splitting more clearly.
1.5
2.4
OHD
A
3H
1.0 PPM
0.5
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Plz plz
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X Achieve > Students: Register X
Assessment - Chem 101 002X
nillanlearning.com/courses/55ace5f9-441e-4942-b91a-6dde768c655e/3/k6bu5e/tools/assessment/items/9f6b56a8-92b9-4b
ent
Check A
LGive Up?
O Hint
OResources
Score:
25
Perform the conversions.
atm
1.196 atm =
860.8 mmHg =
%3D
Pa
1386.9 mmHg :
atm
%3D
287.3 kPa =
%3D
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Please answer both questions.
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O CHEMICAL REACTIONS
Calculating the heat of reaction from molar reaction enthalpy a...
Esth
A chemist measures the energy change AH during the following reaction:
2 Fe,O3(s) → 4 FeO(s)+O2(g)
AH=560. kJ
Use the information to answer the following questions.
O endothermic.
This reaction is...
O exothermic.
Suppose 27.6 g of Fe,O, react.
O Yes, absorbed.
O Yes, released.
Will any heat be released or absorbed?
O No.
If you said heat will
the second part of this question, calculate how
much heat will be released or absorbed.
released or absorbed…
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Part c
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Can you hwlp us with number 4 in attached.. This is not a graded question as it is a practice question . I am 60 years old and helping my son prepare for the AP exam in a few months. We do questions at the back of the textbook by Zumdahl and Zumdahl
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- LEGO History Bookmarks Profiles Window Help - Chapter 8 Homew X b Answered: a, b. C. d. | bartleby x + heducation.com/ext/map/index.html?_con%3Dcon&external_browser%3D0&launchUrl=https%253A%252F%252Flms l Gmail O TCNJ Paws Statistics- Achieve Orgo Connect A Orgo - Aleks French Mind Tap 4G omework Alkyl Halides and Eliminati. G 2 attempts left 券 Check my work What alkyl halide forms the following alkene as the only product in an elimination reaction? Click the "draw structure" button to launch the drawing utility. draw structure Prev 5 of 10 Next > MacBookAirarrow_forwardHome Conte Meas Take G Three Pears Maste G 4.988 Ta X G Three G Three D Spani -> A dmacc.blackboard.com/webapps/assessment/take/launch.jsp?course_assessment_id%= 402371 1&course_id%3 94346 18&ne pps Work for students... O New Tab M Gmail O YouTube A Maps G7 Translate CHM * Question Completion Status: QUESTION 2 Three separate lab groups determined the density of a metal to be 12.5 g/mL, 13.1 g/mL and 14.8 g/mL. Use these values to calculate the average density among the measurements. O A. 13.5 g/mL O B. 30.5 g/mL ОС. 13.1 g/mL O D. 10.1 g/mL QUESTION 3 Three senarate lah grouns determined the density of a metal to be 12.5 g/mL, 13.1 g/mL and 14.8 g/mL. If the accepted dearrow_forwardF2 © Macmillan Learning NO₂ Incorrect # 3 20 F3 : 0: || $ 4 F4 078⁰ % 5 BeCL MacBook Air < 60 & 7arrow_forward
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ISBN:9781305079250
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