lab1.4_20240211_0001

/1 frl- BIO T.2LAB NAMfi: SAMNLT*ACK C*LLf;ffT LAB EXERCISE 1.4: m[ # ]F TYPING ASD HDni REVIEW Check yCIur comprehension of the ,' .:'ial by answering the following questions Genetics *f Bloeid Groups 1. W-hat is the difference between a gene and an allele? r,.*,d t{ $- c? {- fteq T v, q {-' e "1 t/{ t'( 5 ot', f(" {i {, r 6v41. f-$,\6, 4, .,,/, 'i is i'r li- I {.., J 2" What is meant by the phrase "gene for blood type"? How is information stored in a gene? Hsw is it translated into a physical characteristic? \ rt_g g e ir e! rflvcqJAd t'l *'' dt v Yff €,0 .ftSo [to o E I YP€ {* *+rurtc* hv' AM qrne. In .11( -v f4t|rz4p Jf;n(f p h,n dorninant allele, recessive allele, co-JoFrinahce 'l ' * i,rr cqso6,J,{ as " brno 6,. r 3. Define: Hornoaygous, heterozygous, i' , -''.{'::' i , 4. Describe the genetics of blood type determination for the ABO systern: How many alleles are part of the ABS system? What are the different possible genotypes and phenotypes? ' t'/- ' 'f / fr I 1'1 W €*qb\@q bg La^inlqrhtuoz g,f \e+€te7 EoW 1 /g^w

5. Describe the genetics of blood type determination for the Rh system: How many genes and how many alleles are part of the Rh system? Of these, which alleles are of greatest irnportance? Why? Regarding the RhD gene, what are the possible genotypes and phenotypes? /e- UL Tv\e UIt) hts ^\qtbL< n ',.H:fr,}gf ii: Le {-€ (rr G, ' Rt\ S bolds +o< "R"t'r +c Du,?,"1,),r[t\;, ,3,1-$.J type o chird with an 6. What is tl-re probability that an individual heterazygous individualthat has blood type B? g .,/ /, 1C I '/ t '- i-) / qnL & t:g 7. John has blood type B. and his father has blood type 0. John marries a woman with blood type AB. What are the possible blaod types of their children? 3 :l' iro--\ ,' ,r) 'i/r:1'*t..i -( -r- / r r.> j1 P tP{'o# / {: /:._ 1\ i,,.,o l, i ,. I l L_ . ,.')

Dono r- Reci pie nt and M otire r-Fetll s Co rnpatibi I ities 1. ln the ABO hlood group classification cnly {without regard to Rh factor}, a person with type *- blood is called the universal donor because of their laek of appropriate -*. A. AB; cell surface antigens B. AB; antibodies O; cell surface antigens D. 0; antibodies 2. FION is a disease that is treated by transfusing _- blood into the - A. Rh positive; mother ffi' Rh Pesitive; newborn 3. RhoGAM ccnsists of A. Rh positive antigen S *n p*sitive antibodies C. Rh negative; mother m Rh negative; newborn C. Rh negative antigen D. Rh negative antibodies 4. RhoGAM is administered to the for the purpose of A. Newborn, rernoving maternal antihodies B, ltewborn, rernoving rnaternal antrgens C. lVlother, neutralizing fetal antibodies her, neutralizing fetal antigens 5. More than one selection rnay be correct. An AB - person is tested for blood type. We should see agglutination in the drop{s} eontaining: Anti-A Anti-B anti-D nane of these agglutinins D 4 -{ fA- 7a.) Y

6. A sample of hload sent for typing. Agglutination was observed in the drop treated with anti-A, but not anti- B ar anti-D. What is the blood type of this individual? icircle the correct choicei 7, lf the perscn in the question above required a transfusion, circle all the types that woutd he cornpatible donors: 8. The sarne person, at some future date, chcoses to become a blocd donor. Who can receive this generous person's offeri icircle all the types that would be compatible recipients) 9. A person with B + blood has the following antigens on their A. A on[y B. A, Rh C. B only cell membrane: r\ U Rh a E. None of these antigens are present i0. lVlsre than sne selection may be correct. Select all correet chaices. Type O - erythrocytes memhranes capable of stimulating an irnmune response Completely lack surface carbohydrate (oligosaccharide) chains Contain surface carbohydrate chains, but they are missing the terrninal antigenic group Contain surface carbohydrate chains with a terminal antigenic gr"or.rp Contain the integral marker prctein that contains surface loops Lack the integral marker protein that contains surface loops Ll-. Kernicterus is a condition related to A. thyroid disorder' B. oversecretion of adrenal cortical hormones {_ g/ ,fr--\ t) L, D ,sr 1 D.', osmotic imbalances across the cell membrane bitirubin excess folic acid deficiency f L 12. ln the fallowing question, code in ail letters that are correct. An AB negative person is tested for blood type. We should see agglutination in the dropis) contalning: 'A. l anti-A B. anti-B C. anti-D L, 5 A+ ! A- n, B C+ 0- AB+ AB- B. O+ r}_ AS+ AB- I ) Df AE +" l AD- , B+ j