casestudy_jaundice
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Eastern Idaho Technical College *
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100
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Anatomy
Date
Apr 3, 2024
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docx
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2
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Anatomy & Physiology
Name __________________
Mr. Scheffel
Period__________________
Clinical Case Study: Neonatal Jaundice
Case Presentation
Martin and Kim were both twenty-five when they had Michael, their first child. Kim remained very healthy during her pregnancy and went into labor at 9:00 a.m., just 3 days after her due date. Delivery went quite smoothly, and that evening, mother and child rested comfortably. Two days later, Kim and Michael were released from the hospital. That evening at feeding time, Kim noticed that the whites of Michael's eyes seemed just slightly yellow, a condition that worsened noticeably by the next morning. Kim called the pediatrician and made an appointment for that morning.
Upon examining Michael, the pediatrician informed Martin and Kim that the infant had neonatal jaundice, a condition quite common in newborns and one that need not cause them too much concern. The physician explained that neonatal jaundice was the result of the normal
destruction of old or worn fetal red blood cells and the inability of the newborn's liver to effectively process bilirubin, a chemical produced when red blood cells are destroyed. The physician told the parents he would like to see Michael every other day in order to monitor blood bilirubin concentration until the bilirubin concentration dropped into the normal range. He recommended that Kim feed Michael frequently and instructed them to place Michael in sunlight whenever possible.
Case Background
Neonatal jaundice is a disorder that affects nearly 50% of all newborns to at least a small degree. The yellow coloration of the skin and sclera of the eyes is due to the accumulation of bilirubin in adipose tissue and its adherence to collagen fibers. In neonatal jaundice, the excess
bilirubin is not due to an abnormal level of red blood cell destruction. It is due to the inability of
the young liver cells to conjugate bilirubin, or make it soluble in bile, so that it can be excreted and removed from the body by the digestive tract. This inability is corrected, usually within one week, as the liver cells synthesize the conjugation enzymes. If uncorrected, sufficiently high bilirubin concentrations can cause brain damage. Frequent feedings of a newborn with jaundice increase gastrointestinal tract motility and decrease the likelihood of reabsorbing significant amounts of bilirubin in the small intestine. Radiation from sunlight alters the chemical form of bilirubin, making it easier for the liver to excrete.
Analysis Questions
:
1. Which organs are primarily responsible for removing old or worn red blood cells from circulation?
2. Discuss how the normal breakdown of hemoglobin relates to neonatal jaundice?
Anatomy & Physiology
Name __________________
Mr. Scheffel
Period__________________
3. Why are parents of newborns with jaundice instructed by doctors to feed them frequently and expose them to sunlight?
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