SEELEY'S ANATOMY+PHYSIOLOGY
SEELEY'S ANATOMY+PHYSIOLOGY
12th Edition
ISBN: 9781260172195
Author: VanPutte
Publisher: RENT MCG
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Chapter 6.10, Problem 40AYP

What effect does aging hove on the quality and quantity of bone matrix?

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. Consider a base substitution mutation that occurred in a DNA sequence that resulted in a change in the encoded protein from the amino acid glutamic acid to aspartic acid. Normally the glutamic acid amino acid is located on the outside of the soluble protein but not near an active site. O-H¨ A. What type of mutation occurred? O-H B. What 2 types of chemical bonds are found in the R-groups of each amino acid? The R groups are shaded. CH2 CH2 CH2 H2N-C-COOH H2N-C-COOH 1 H Glutamic acid H Aspartic acid C. What 2 types of bonds could each R-group of each of these amino acids form with other molecules? D. Consider the chemical properties of the two amino acids and the location of the amino acid in the protein. Explain what effect this mutation will have on this protein's function and why.
engineered constructs that consist of hollow fibers are acting as synthetic capillaries, around which cells have been loaded. The cellular space around a single fiber can be modeled as if it were a Krogh tissue cylinder. Each fiber has an outside “capillary” radius of 100 µm and the “tissue” radius can be taken as 200 µm. The following values apply to the device:R0 = 20 µM/secaO2 = 1.35 µM/mmHgDO2,T = 1.67 x 10-5 cm2/secPO2,m = 4 x 10-3 cm/secInstead of blood inside the fibers, the oxygen transport and tissue consumption are being investigated by usingan aqueous solution saturated with pure oxygen. As a result, there is no mass transfer resistance in the synthetic“capillary”, only that due to the membrane itself. Rather than accounting for pO2 variations along the length ofthe fiber, use an average value in the “capillary” of 130 mmHg.Is the tissue fully oxygenated?

Chapter 6 Solutions

SEELEY'S ANATOMY+PHYSIOLOGY

Ch. 6.3 - Describe the structure of spongy bone. What are...Ch. 6.3 - Describe the structure of compact bone. What is an...Ch. 6.3 - Trace the pathway nutrients must follow from blood...Ch. 6.4 - List the four basic shapes of bones, and give an...Ch. 6.4 - Sketch and lable the parts of a typical long bone.Ch. 6.4 - Where are the periosteum and endosteum located,...Ch. 6.4 - What are red and yellow bone marrows? Where are...Ch. 6.4 - Compare the structure of a long bone with those of...Ch. 6.5 - Describe the formation of spongy and compact bone...Ch. 6.5 - For the process of endochondral ossification,...Ch. 6.5 - When do primary and secondary Ossification centers...Ch. 6.5 - What bones, or parts of bones, are formed from...Ch. 6.6 - Name and describe the events occurring in the four...Ch. 6.6 - Explain the process of growth at the articular...Ch. 6.6 - Describe how new osteons are produced as a bone...Ch. 6.6 - Prob. 26AYPCh. 6.6 - Prob. 27AYPCh. 6.6 - Prob. 28AYPCh. 6.7 - Why is it important for bone remodeling to occur?Ch. 6.7 - What is a basic multicellular unit (BMU)? Explain...Ch. 6.7 - Prob. 31AYPCh. 6.8 - What are the four steps of bone repair?Ch. 6.8 - Prob. 33AYPCh. 6.8 - Distinguish between the location and composition...Ch. 6.8 - Prob. 35AYPCh. 6.9 - Prob. 36AYPCh. 6.9 - Prob. 37AYPCh. 6.9 - Prob. 38AYPCh. 6.9 - Prob. 39AYPCh. 6.10 - What effect does aging hove on the quality and...Ch. 6.10 - Prob. 41AYPCh. 6 - Prob. 1RACCh. 6 - Chondrocytes are mature cartilage cells within the...Ch. 6 - Which of these statements concerning cartilage is...Ch. 6 - Prob. 4RACCh. 6 - Prob. 5RACCh. 6 - Prob. 6RACCh. 6 - Prob. 7RACCh. 6 - Prob. 8RACCh. 6 - Prob. 9RACCh. 6 - Prob. 10RACCh. 6 - Prob. 11RACCh. 6 - The periosteum a. is an epithelial tissue...Ch. 6 - Prob. 13RACCh. 6 - Prob. 14RACCh. 6 - Prob. 15RACCh. 6 - Prob. 16RACCh. 6 - Prob. 17RACCh. 6 - During growth in length of a long bone, cartilage...Ch. 6 - Prob. 19RACCh. 6 - Prob. 20RACCh. 6 - Prob. 21RACCh. 6 - Bone remodelling can occur When woven bone is...Ch. 6 - Given these processes: (1) cartilage ossification...Ch. 6 - Which of these processes during bone repair...Ch. 6 - Prob. 25RACCh. 6 - Prob. 1CTCh. 6 - Explain why running helps prevent osteoporosis in...Ch. 6 - Prob. 3CTCh. 6 - Prob. 4CTCh. 6 - Prob. 5CTCh. 6 - Prob. 6CT
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