
Concept explainers
Introduction:
The pore-forming membrane proteins are referred to as ion channels, which permit the movement of ion across the membrane. In the axonal membrane, channels are present for potassium ion (K+) and sodium ions (Na+). Their main functions include establishing a resting membrane potential of -70mV in absence of signal and producing action potential after stimulation.

Answer to Problem 1TYK
Correct answer:
The neurons have a significantly larger number of potassium leaky channels, which facilitate the leakage of potassium ion across the membrane. These ions help to create the resting potential.
Explanation of Solution
Explanation/Justification for the correct answer:
Option (b) is given as potassium ion (K+) help to create the resting potential. The axonal membrane is almost impermeable to all cations except potassium ion. Thus the K+ will leak from the membrane along its
Explanation for incorrect answers:
Option (a) is given as calcium ions (Ca2+). The leakage of Ca2+ ions does not occur in order to achieve the resting potential as the concentration gradient for Ca2+ ions is not created by the sodium–potassium pump. So, it is a wrong answer.
Option (c) is given as sodium ions (Na+). The number of leak channels for Na+ ions is comparatively less than that for potassium ions. They are present on the outer side of the membrane; their inward movement does not create resting membrane potential. So, it is a wrong answer.
Option (d) is given as chloride ions (Cl-). The number of leaky channels for Cl- is very less. So, it is a wrong answer.
Hence, options (a), (c), and (d) are incorrect.
Therefore, it can be concluded that the potassium ions leak across the neuron’s membrane and thereby create the resting membrane potential.
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